Genomic-based precision medicine has not only improved tumour therapy but has also
shown its weaknesses. Genomic profiling and mutation analysis have identified alterations …

Background The incidence of skin cancer is currently increasing, and conventional treatment
options inadequately address the demands of disease management. Fortunately, the recent …

Abstract Anti–PD-L1–based combination immunotherapy has become the first-line treatment
for unresectable hepatocellular carcinoma (HCC). However, the objective response rate is …

Background Non-muscle invasive bladder cancer (NMIBC) is one of the most common
malignant tumors of the urinary system. There is an urgent need for further studies to …

Background Chordomas are rare osseous neoplasms with a dismal prognosis when they
recur. Here we identified cell surface proteins that could potentially serve as novel …

Introduction Uterine spiral artery remodeling is the prerequisite for ensuring adequate blood
supply to the maternal-fetal interface during human pregnancy. One crucial cellular event in …

Introduction In recent years, immunotherapy has shown significant therapeutic potential in
patients with advanced tumors. However, only a small number of individuals benefit, mainly …

Chordoma, as a rare, low-grade malignant tumor that tends to occur in the midline of the
body, grows slowly but often severely invades surrounding tissues and bones. Due to the …

Chordomas are tumors thought to originate from notochordal remnants that occur in midline
structures from the cloves of the skull base to the sacrum. In adults, the most common …

Abstract Ethnopharmacological relevance Pseudostellaria heterophylla (Miq.) Pax (PH) is a
traditional folk medicine, which is widely used clinically for digestive system tumors such as …