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Astrocyte endfeet in brain function and pathology: open questions
Astrocyte endfeet enwrap the entire vascular tree within the central nervous system, where
they perform important functions in regulating the blood-brain barrier (BBB), cerebral blood …
they perform important functions in regulating the blood-brain barrier (BBB), cerebral blood …
Astrocyte morphology
KT Baldwin, KK Murai, BS Khakh - Trends in cell biology, 2024 - cell.com
Astrocytes are predominant glial cells that tile the central nervous system (CNS). A cardinal
feature of astrocytes is their complex and visually enchanting morphology, referred to as …
feature of astrocytes is their complex and visually enchanting morphology, referred to as …
Identification of region-specific astrocyte subtypes at single cell resolution
Astrocytes, a major cell type found throughout the central nervous system, have general
roles in the modulation of synapse formation and synaptic transmission, blood–brain barrier …
roles in the modulation of synapse formation and synaptic transmission, blood–brain barrier …
The blood–brain barrier: composition, properties, and roles in brain health
Blood vessels are critical to deliver oxygen and nutrients to tissues and organs throughout
the body. The blood vessels that vascularize the central nervous system (CNS) possess …
the body. The blood vessels that vascularize the central nervous system (CNS) possess …
[HTML][HTML] Single-cell delineation of lineage and genetic identity in the mouse brain
During neurogenesis, mitotic progenitor cells lining the ventricles of the embryonic mouse
brain undergo their final rounds of cell division, giving rise to a wide spectrum of postmitotic …
brain undergo their final rounds of cell division, giving rise to a wide spectrum of postmitotic …
Reactive astrocytes and emerging roles in central nervous system (CNS) disorders
SA Liddelow, ML Olsen… - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
In addition to their many functions in the healthy central nervous system (CNS), astrocytes
respond to CNS damage and disease through a process called “reactivity.” Recent evidence …
respond to CNS damage and disease through a process called “reactivity.” Recent evidence …
Neurovascular coupling in development and disease: focus on astrocytes
TL Stackhouse, A Mishra - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Neurovascular coupling is a crucial mechanism that matches the high energy demand of the
brain with a supply of energy substrates from the blood. Signaling within the neurovascular …
brain with a supply of energy substrates from the blood. Signaling within the neurovascular …
A closer look at astrocyte morphology: Development, heterogeneity, and plasticity at astrocyte leaflets
B Torres-Ceja, ML Olsen - Current Opinion in Neurobiology, 2022 - Elsevier
Astrocytes represent an abundant type of glial cell involved in nearly every aspect of central
nervous system (CNS) function, including synapse formation and maturation, ion and …
nervous system (CNS) function, including synapse formation and maturation, ion and …
Astrocyte heterogeneity and interactions with local neural circuits
MG Holt - Essays in Biochemistry, 2023 - portlandpress.com
Astrocytes are ubiquitous within the central nervous system (CNS). These cells possess
many individual processes which extend out into the neuropil, where they interact with a …
many individual processes which extend out into the neuropil, where they interact with a …
[HTML][HTML] Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development
Neuron-glia interactions play a critical role in the regulation of synapse formation and circuit
assembly. Here we demonstrate that canonical Sonic hedgehog (Shh) pathway signaling in …
assembly. Here we demonstrate that canonical Sonic hedgehog (Shh) pathway signaling in …