Astrocyte endfeet in brain function and pathology: open questions

B Díaz-Castro, S Robel, A Mishra - Annual review of …, 2023 - annualreviews.org
Astrocyte endfeet enwrap the entire vascular tree within the central nervous system, where
they perform important functions in regulating the blood-brain barrier (BBB), cerebral blood …

Astrocyte morphology

KT Baldwin, KK Murai, BS Khakh - Trends in cell biology, 2024 - cell.com
Astrocytes are predominant glial cells that tile the central nervous system (CNS). A cardinal
feature of astrocytes is their complex and visually enchanting morphology, referred to as …

Identification of region-specific astrocyte subtypes at single cell resolution

MY Batiuk, A Martirosyan, J Wahis, F de Vin… - Nature …, 2020 - nature.com
Astrocytes, a major cell type found throughout the central nervous system, have general
roles in the modulation of synapse formation and synaptic transmission, blood–brain barrier …

The blood–brain barrier: composition, properties, and roles in brain health

B Lacoste, A Prat… - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
Blood vessels are critical to deliver oxygen and nutrients to tissues and organs throughout
the body. The blood vessels that vascularize the central nervous system (CNS) possess …

[HTML][HTML] Single-cell delineation of lineage and genetic identity in the mouse brain

RC Bandler, I Vitali, RN Delgado, MC Ho… - Nature, 2022 - nature.com
During neurogenesis, mitotic progenitor cells lining the ventricles of the embryonic mouse
brain undergo their final rounds of cell division, giving rise to a wide spectrum of postmitotic …

Reactive astrocytes and emerging roles in central nervous system (CNS) disorders

SA Liddelow, ML Olsen… - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
In addition to their many functions in the healthy central nervous system (CNS), astrocytes
respond to CNS damage and disease through a process called “reactivity.” Recent evidence …

Neurovascular coupling in development and disease: focus on astrocytes

TL Stackhouse, A Mishra - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Neurovascular coupling is a crucial mechanism that matches the high energy demand of the
brain with a supply of energy substrates from the blood. Signaling within the neurovascular …

A closer look at astrocyte morphology: Development, heterogeneity, and plasticity at astrocyte leaflets

B Torres-Ceja, ML Olsen - Current Opinion in Neurobiology, 2022 - Elsevier
Astrocytes represent an abundant type of glial cell involved in nearly every aspect of central
nervous system (CNS) function, including synapse formation and maturation, ion and …

Astrocyte heterogeneity and interactions with local neural circuits

MG Holt - Essays in Biochemistry, 2023 - portlandpress.com
Astrocytes are ubiquitous within the central nervous system (CNS). These cells possess
many individual processes which extend out into the neuropil, where they interact with a …

[HTML][HTML] Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development

Y **e, AT Kuan, W Wang, ZT Herbert, O Mosto… - Cell reports, 2022 - cell.com
Neuron-glia interactions play a critical role in the regulation of synapse formation and circuit
assembly. Here we demonstrate that canonical Sonic hedgehog (Shh) pathway signaling in …