The human genetic epidemiology of COVID-19

MEK Niemi, MJ Daly, A Ganna - Nature Reviews Genetics, 2022 - nature.com
Human genetics can inform the biology and epidemiology of coronavirus disease 2019
(COVID-19) by pinpointing causal mechanisms that explain why some individuals become …

The contribution of Neanderthal introgression to modern human traits

PF Reilly, A Tjahjadi, SL Miller, JM Akey, S Tucci - Current Biology, 2022 - cell.com
Neanderthals, our closest extinct relatives, lived in western Eurasia from 400,000 years ago
until they went extinct around 40,000 years ago. DNA retrieved from ancient specimens …

Post-acute COVID-19 syndrome in patients after 12 months from COVID-19 infection in Korea

Y Kim, SW Kim, HH Chang, KT Kwon, S Bae… - BMC infectious …, 2022 - Springer
Background As the coronavirus disease 2019 (COVID-19) pandemic continues to progress,
awareness about its long-term impacts has been growing. To date, studies on the long-term …

Dissecting human population variation in single-cell responses to SARS-CoV-2

Y Aquino, A Bisiaux, Z Li, M O'Neill, J Mendoza-Revilla… - Nature, 2023 - nature.com
Humans display substantial interindividual clinical variability after SARS-CoV-2 infection,–,
the genetic and immunological basis of which has begun to be deciphered. However, the …

[KNIHA][B] COVID societies: Theorising the coronavirus crisis

D Lupton - 2022 - taylorfrancis.com
COVID Societies presents a compelling and accessible overview of key sociocultural
theories that can help us make sense of the diverse, dynamic and complex elements of the …

A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection

E Andreakos, L Abel, DC Vinh, E Kaja, BA Drolet… - Nature …, 2022 - nature.com
SARS-CoV-2 infections display tremendous interindividual variability, ranging from
asymptomatic infections to life-threatening disease. Inborn errors of, and autoantibodies …

Understanding the evolution of immune genes in jawed vertebrates

M Vinkler, SR Fiddaman, M Těšický… - Journal of …, 2023 - academic.oup.com
Driven by co‐evolution with pathogens, host immunity continuously adapts to optimize
defence against pathogens within a given environment. Recent advances in genetics …

SARS‐CoV‐2 biology and variants: anticipation of viral evolution and what needs to be done

R Luo, A Delaunay‐Moisan, K Timmis… - Environmental …, 2021 - Wiley Online Library
The global propagation of SARS‐CoV‐2 and the detection of a large number of variants,
some of which have replaced the original clade to become dominant, underscores the fact …

A mechanistic evolutionary model explains the time-dependent pattern of substitution rates in viruses

M Ghafari, P Simmonds, OG Pybus, A Katzourakis - Current Biology, 2021 - cell.com
Estimating viral timescales is fundamental in understanding the evolutionary biology of
viruses. Molecular clocks are widely used to reveal the recent evolutionary histories of …

Local adaptation and archaic introgression shape global diversity at human structural variant loci

SM Yan, RM Sherman, DJ Taylor, DR Nair, AN Bortvin… - Elife, 2021 - elifesciences.org
Large genomic insertions and deletions are a potent source of functional variation, but are
challenging to resolve with short-read sequencing, limiting knowledge of the role of such …