Abstract P-glycoprotein (P-gp) is an ATP-dependent efflux pump encoded by the MDR1
gene in humans, known to mediate multidrug resistance of neoplastic cells to cancer …

Adenosine triphosphate (ATP)-binding cassette (ABC) transporters are highly expressed in
tumor cells, as well as in organs involved in absorption and secretion processes, mediating …

Indian stingless bee propolis has a complex chemical nature and is reported to possess
various medicinal properties. In the present study, anticancer activity of the ethanolic extract …

Various platforms have been developed as innovative nanocarriers to deliver therapeutic
agents to the diseased sites. Multifunctional surface modification allows an enhanced …

The detoxification of toxic substances is of general relevance in all biological systems. The
plethora of exogenous xenobiotic compounds and endogenous toxic metabolic products …

Flavonoids are a class of polyphenol antioxygen, despite various known biological activities
and therapeutic potential, scattered but not much is known about their interactions with drug …

The present study investigated the lipogenesis inhibition effect of mulberry leaf polyphenols
(MLPP), polysaccharides (MLPS), polyphenols-polysaccharides complex (PPPS, with a total …

Several evidences suggest that enhanced oxidative stress is involved in the pathogenesis
and/or progression of several neurodegenerative diseases. The aim of this study was to …

H 1-antihistamines are widely used in treating allergic disorders, eg, conjunctivitis, urticaria,
dermatitis and asthma. The first-generation H 1-antihistamines have a much greater …

Multidrug resistance (MDR) mediated by ATP binding cassette subfamily B member 1
(ABCB1) is significantly hindering effective cancer chemotherapy. However, currently, no …