DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …

With numerous recent advances, the field of therapeutic nucleic acid nanotechnology is now
poised for clinical translation supported by several examples of FDA-approved nucleic acid …

DNA origami may enable more versatile gene delivery applications through its ability to
create custom nanoscale objects with specific targeting, cell-invading, and intracellular …

Three-dimensional wireframe DNA origami have programmable structural and sequence
features that render them potentially suitable for prophylactic and therapeutic applications …

Broad-spectrum anti-SARS-CoV-2 strategies that can inhibit the infection of wild-type and
mutant strains would alleviate their threats to global public health. Here, we propose an …

Viral capsids can adopt various geometries, most iconically characterized by icosahedral or
helical symmetries. Importantly, precise control over the size and shape of virus capsids …

Protein-based virus-like particles (P-VLPs) are commonly used to spatially organize
antigens and enhance humoral immunity through multivalent antigen display. However, P …

Origami-inspired metamaterials and structures exhibit extraordinary properties, including
programmable Poisson's ratio and tunable stiffness. Although some research has achieved …

Viruslike particles (VLPs) fabricated using wireframe DNA origami are emerging as
promising vaccine and gene therapeutic delivery platforms due to their programmable …

DNA nanotechnology is a unique field, where physics, chemistry, biology, mathematics,
engineering, and materials science can elegantly converge. Since the original proposal of …