The arms race between bacteria and their phage foes

HG Hampton, BNJ Watson, PC Fineran - Nature, 2020 - nature.com
Bacteria are under immense evolutionary pressure from their viral invaders—
bacteriophages. Bacteria have evolved numerous immune mechanisms, both innate and …

Antibiotic resistance genes in bacteria: Occurrence, spread, and control

Z Jian, L Zeng, T Xu, S Sun, S Yan… - Journal of basic …, 2021 - Wiley Online Library
The production and use of antibiotics are becoming increasingly common worldwide, and
the problem of antibiotic resistance is increasing alarmingly. Drug‐resistant infections …

Mutualistic interplay between bacteriophages and bacteria in the human gut

AN Shkoporov, CJ Turkington, C Hill - Nature Reviews Microbiology, 2022 - nature.com
Bacteriophages (phages) are often described as obligate predators of their bacterial hosts,
and phage predation is one of the leading forces controlling the density and distribution of …

[HTML][HTML] New insights into intestinal phages

R Sausset, MA Petit, V Gaboriau-Routhiau… - Mucosal …, 2020 - Elsevier
The intestinal microbiota plays important roles in human health. This last decade, the viral
fraction of the intestinal microbiota, composed essentially of phages that infect bacteria …

Understanding the impacts of bacteriophage viruses: from laboratory evolution to natural ecosystems

B Koskella, CA Hernandez… - Annual Review of …, 2022 - annualreviews.org
Viruses of bacteria (bacteriophages or phage) have broad effects on bacterial ecology and
evolution in nature that mediate microbial interactions, shape bacterial diversity, and …

Gut bacteriophage: current understanding and challenges

TDS Sutton, C Hill - Frontiers in endocrinology, 2019 - frontiersin.org
The gut microbiome is widely accepted to have a significant impact on human health yet,
despite years of research on this complex ecosystem, the contributions of different forces …

The gut virome is associated with stress-induced changes in behaviour and immune responses in mice

NL Ritz, LA Draper, TFS Bastiaanssen… - Nature …, 2024 - nature.com
The microbiota–gut–brain axis has been shown to play an important role in the stress
response, but previous work has focused primarily on the role of the bacteriome. The gut …

The human gut phage community and its implications for health and disease

P Manrique, M Dills, MJ Young - Viruses, 2017 - mdpi.com
In this review, we assess our current understanding of the role of bacteriophages infecting
the human gut bacterial community in health and disease. In general, bacteriophages …

The gut and Parkinson's disease—a bidirectional pathway

SF Santos, HL De Oliveira, ES Yamada… - Frontiers in …, 2019 - frontiersin.org
Humans evolved a symbiotic relationship with their gut microbiome, a complex microbial
community composed of bacteria, archaea, protists, and viruses, including bacteriophages …

Bacterial 'grounded'prophages: hotspots for genetic renovation and innovation

BCM Ramisetty, PA Sudhakari - Frontiers in genetics, 2019 - frontiersin.org
Bacterial genomes are highly plastic allowing the generation of variants through mutations
and acquisition of genetic information. The fittest variants are then selected by the econiche …