The role of microRNAs in the gastric cancer tumor microenvironment
X Yu, Y Zhang, F Luo, Q Zhou, L Zhu - Molecular cancer, 2024 - Springer
Background Gastric cancer (GC) is one of the deadliest malignant tumors with unknown
pathogenesis. Due to its treatment resistance, high recurrence rate, and lack of reliable early …
pathogenesis. Due to its treatment resistance, high recurrence rate, and lack of reliable early …
Natural killer cells as key players of tumor progression and angiogenesis: old and novel tools to divert their pro-tumor activities into potent anti-tumor effects
Immune cells, as a consequence of their plasticity, can acquire altered phenotype/functions
within the tumor microenvironment (TME). Some of these aberrant functions include …
within the tumor microenvironment (TME). Some of these aberrant functions include …
Essential role of microRNA-155 in regulating endothelium-dependent vasorelaxation by targeting endothelial nitric oxide synthase
HX Sun, DY Zeng, RT Li, RP Pang, H Yang, YL Hu… - …, 2012 - ahajournals.org
Nitric oxide generated by endothelial nitric oxide synthase (eNOS) plays an important role in
maintaining cardiovascular homeostasis. Under various pathological conditions, abnormal …
maintaining cardiovascular homeostasis. Under various pathological conditions, abnormal …
The microRNA miR-155 controls CD8+ T cell responses by regulating interferon signaling
DT Gracias, E Stelekati, JL Hope, AC Boesteanu… - Nature …, 2013 - nature.com
We found upregulation of expression of the microRNA miR-155 in primary effector and
effector memory CD8+ T cells, but low miR-155 expression in naive and central memory …
effector memory CD8+ T cells, but low miR-155 expression in naive and central memory …
Role of miRNAs in immune responses and immunotherapy in cancer
In the past decade, the study of mechanisms of cancer immunity has seen a prominent
boom, which paralleled the increased amount of research on the clinical efficacy of immune …
boom, which paralleled the increased amount of research on the clinical efficacy of immune …
Physiological roles of miR‐155
R Mashima - Immunology, 2015 - Wiley Online Library
Summary miR‐155 is involved in non‐coding microRNAs found in humans, mice and
chickens of which the sequence is conserved. Historically, miR‐155 was identified as a B …
chickens of which the sequence is conserved. Historically, miR‐155 was identified as a B …
MicroRNA-155 and antiviral immune responses
The microRNA, miR-155 regulates both adaptive and innate immune responses. In viral
infections, miR-155 can affect both innate immunity (interferon response, natural killer cell …
infections, miR-155 can affect both innate immunity (interferon response, natural killer cell …
Metabolic regulation of natural killer cell IFN-γ production
AY Mah, MA Cooper - Critical Reviews™ in Immunology, 2016 - dl.begellhouse.com
Metabolism is critical for a host of cellular functions and provides a source of intracellular
energy. It has been recognized recently that metabolism also regulates differentiation and …
energy. It has been recognized recently that metabolism also regulates differentiation and …
Clinical significance of miRNAs in autoimmunity
MicroRNAs (miRNAs) are evolutionally conserved, single-stranded RNAs that regulate gene
expression at the posttranscriptional level by disrupting translation. MiRNAs are key players …
expression at the posttranscriptional level by disrupting translation. MiRNAs are key players …
Gene expression profiling for the identification and classification of antibody-mediated heart rejection
Background: Antibody-mediated rejection (AMR) contributes to heart allograft loss. However,
an important knowledge gap remains in terms of the pathophysiology of AMR and how …
an important knowledge gap remains in terms of the pathophysiology of AMR and how …