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Synthetic cells revisited: Artificial cell construction using polymeric building blocks
The exponential growth of research on artificial cells and organelles underscores their
potential as tools to advance the understanding of fundamental biological processes. The …
potential as tools to advance the understanding of fundamental biological processes. The …
Polymersomes for therapeutic protein and peptide delivery: towards better loading properties
C Hua, L Qiu - International Journal of Nanomedicine, 2024 - Taylor & Francis
Therapeutics based on proteins and peptides have profoundly transformed the landscape of
treatment for diseases, from diabetes mellitus to cancers, yet the short half-life and low …
treatment for diseases, from diabetes mellitus to cancers, yet the short half-life and low …
Protocells Capable of Generating a Cytoskeleton‐Like Structure from Intracellular Membrane‐Active Artificial Organelles
The intricate nature of eukaryotic cells with intracellular compartments having differences in
component concentration and viscosity in their lumen provides (membrane‐active) enzymes …
component concentration and viscosity in their lumen provides (membrane‐active) enzymes …
Protein–polymer bioconjugation, immobilization, and encapsulation: a comparative review towards applicability, functionality, activity, and stability
Polymer-based biomaterials have received a lot of attention due to their biomedical,
agricultural, and industrial potential. Soluble protein–polymer bioconjugates, immobilized …
agricultural, and industrial potential. Soluble protein–polymer bioconjugates, immobilized …
Stretched or wrinkled? Looking into the polymer conformation within polymersome membranes
C Effenberg, J Gaitzsch - Soft Matter, 2024 - pubs.rsc.org
Self-assembly of amphiphilic block-copolymers into polymersomes is a well-established
concept. In this membrane, the hydrophilic part is considered to be loosely assembled …
concept. In this membrane, the hydrophilic part is considered to be loosely assembled …
Advancing Artificial Cells with Functional Compartmentalized Polymeric Systems-In Honor of Wolfgang Meier
The fundamental building block of living organisms is the cell, which is the universal
biological base of all living entities. This micrometric mass of cytoplasm and the membrane …
biological base of all living entities. This micrometric mass of cytoplasm and the membrane …
Multimodal Imaging, Drug Delivery, and On‐Board Triggered Degradation in Soft Capsule Rolling Microrobots
D Castellanos‐Robles, RCLM Doineau… - Advanced Intelligent …, 2024 - Wiley Online Library
In the rapidly advancing field of medical microrobotics, designing robots capable of
addressing various challenges—such as imaging, biodegradation, and multifunctionality—is …
addressing various challenges—such as imaging, biodegradation, and multifunctionality—is …
Facile approach to fabricate stable multi-chamber colloid particles for compartmentalized encapsulation and reaction control of incompatible molecules
H Chen, M Hu, X Tan, X Han, J Gao, L Ma… - Chemical Engineering …, 2023 - Elsevier
Compartmentalized delivery systems can achieve simultaneous encapsulation of multiple
guest cargos in independent spaces and are becoming a topic of tremendous interest in …
guest cargos in independent spaces and are becoming a topic of tremendous interest in …
Reversible crowdedness of pH-responsive and host–guest active polymersomes: Mimicking µm-sized cell structures
The structure–function characteristics of isolated artificial organelles (AOs) in protocells are
mainly known, but there are few reports on clustered or aggregated AOs. To imitate µm …
mainly known, but there are few reports on clustered or aggregated AOs. To imitate µm …
Stable and permeable polyion complex vesicles designed as enzymatic nanoreactors
Y Wan, Y Qiu, J Zhou, J Liu, MAC Stuart, Y Peng… - Soft Matter, 2024 - pubs.rsc.org
Polymeric vesicles are perspective vehicles for fabricating enzymatic nanoreactors towards
diverse biomedical and catalytic applications, yet the design of stable and permeable …
diverse biomedical and catalytic applications, yet the design of stable and permeable …