Virus‐like particles (VLPs) mimic the whole construct of virus particles devoid of viral
genome as used in subunit vaccine design. VLPs can elicit efficient protective immunity as …

Vaccination is one of the most effective interventions in global health. The worldwide
vaccination programs significantly reduced the number of deaths caused by infectious …

The production of pharmaceutical compounds in plants is attracting increasing attention, as
plant-based systems can be less expensive, safer, and more scalable than mammalian …

Virus-like particles (VLPs) are multiprotein structures that resemble the conformation of
native viruses but lack a viral genome, potentiating their application as safer and cheaper …

Protein therapeutics is a rapidly growing segment of the pharmaceutical market. Currently,
the majority of protein therapeutics are manufactured in mammalian cells for their ability to …

Abstract Background Spodoptera frugiperda (Sf-9) cells are often used to produce
recombinant proteins by transient expression. The culture medium contributes to the …

Adaptive laboratory evolution (ALE) has been extensively used to modulate the phenotype
of industrial model organisms (eg Escherichia. coli and Saccharomyces cerevisae) towards …

Safer and broadly protective vaccines are needed to cope with the continuous evolution of
circulating influenza virus strains and promising approaches based on the expression of …

Insect cells have shown a high versatility to produce multiple recombinant products. The
ease of culture, low contamination risk with human pathogens and high expression capacity …

The cell lines derived from the fall armyworm (FAW), Spodoptera frugiperda, have been
widely used for production of recombinant proteins for applications in both basic research …