Valproic acid (VPA) and its salts are psychotropic drugs that are widely used in neurological
diseases (epilepsy, neuropathic pain, migraine, etc.) and psychiatric disorders …

Valproic acid is an anticonvulsant and mood-stabilizing drug used primarily in the treatment
of epilepsy and bipolar disorder. Adverse effects of valproic acid are rare, but hepatotoxicity …

Novel and combinatorial treatment methods are becoming sought after entities in cancer
treatment and these treatments are even more valuable for pancreatic cancer. The scientists …

Histone deacetylase inhibitors (HDIs) are promising anticancer drugs, which inhibit
proliferation of a wide variety of cancer cells including breast carcinoma cells. In the present …

Chalcones are a group of molecules with a broad spectrum of biological activities, being
especially appealing for their antiproliferative effects on several cancer cell lines. For this …

Simple Summary Although in the last decades the clinical outcome of cancer patients
considerably improved, the major drawbacks still associated with chemotherapy are the …

Abstract Background Long non-coding RNAs (lncRNAs) are transcribed pervasively in the
genome and act to regulate chromatin remodeling and gene expression. Dysregulated …

Histone deacetylase inhibitors (HDIs) are a new class of drugs which affect the activity of
HDACs resulting in changed of acetylation in many proteins. HDIs can induce differentiation …

Dysregulation of long non-coding RNAs (lncRNAs) has been known to be relevant to the
progression of human cancers, including neuroblastoma (NB). Small nucleolar RNA host …

Altered glucose metabolism is a hallmark for cancer, which is characterized by a unique
metabolic phenotype known as Warburg effect or aerobic glycolysis. Emerging studies show …