[HTML][HTML] Glycosylation and behavioral symptoms in neurological disorders

P Pradeep, H Kang, B Lee - Translational Psychiatry, 2023 - nature.com
Glycosylation, the addition of glycans or carbohydrates to proteins, lipids, or other glycans, is
a complex post-translational modification that plays a crucial role in cellular function. It is …

Native top‐down mass spectrometry for higher‐order structural characterization of proteins and complexes

R Liu, S **a, H Li - Mass spectrometry reviews, 2023 - Wiley Online Library
Progress in structural biology research has led to a high demand for powerful and yet
complementary analytical tools for structural characterization of proteins and protein …

Recent advances in the analysis of complex glycoproteins

S Gaunitz, G Nagy, NLB Pohl, MV Novotny - Analytical chemistry, 2017 - ACS Publications
Notes 408 Biographies 408 Acknowledgments 409 References 409 The enormous
structural diversity of glycoconjugates mirrors their myriad biological functions in prokaryotic …

Isomeric separation of N-glycopeptides derived from glycoproteins by porous graphitic carbon (PGC) LC-MS/MS

R Zhu, Y Huang, J Zhao, J Zhong… - Analytical chemistry, 2020 - ACS Publications
Protein glycosylation is involved in many biological processes and physiological functions.
Despite the recent advances in LC-MS/MS methodologies, the profiling of site-specific …

Clinically relevant post-translational modification analyses—maturing workflows and bioinformatics tools

D Pascovici, JX Wu, MJ McKay, C Joseph… - International journal of …, 2018 - mdpi.com
Post-translational modifications (PTMs) can occur soon after translation or at any stage in
the lifecycle of a given protein, and they may help regulate protein folding, stability, cellular …

Advances in neuroproteomics for neurotrauma: unraveling insights for personalized medicine and future prospects

F Kobeissy, M Goli, H Yadikar, Z Shakkour… - Frontiers in …, 2023 - frontiersin.org
Neuroproteomics, an emerging field at the intersection of neuroscience and proteomics, has
garnered significant attention in the context of neurotrauma research. Neuroproteomics …

Targeted O‐glycoproteomics explored increased sialylation and identified MUC16 as a poor prognosis biomarker in advanced‐stage bladder tumours

S Cotton, R Azevedo, C Gaiteiro, D Ferreira… - Molecular …, 2017 - Wiley Online Library
Bladder carcinogenesis and tumour progression is accompanied by profound alterations in
protein glycosylation on the cell surface, which may be explored for improving disease …

Photocrosslinking probes for capture of carbohydrate interactions

H Wu, J Kohler - Current opinion in chemical biology, 2019 - Elsevier
Glycan-mediated interactions are essential in many biological processes and regulate a
wide variety of cellular functions. However, characterizing these interactions is difficult …

Clinical relevance of biomarkers, new therapeutic approaches, and role of post-translational modifications in the pathogenesis of Alzheimer's disease

I Mumtaz, MO Ayaz, MS Khan, U Manzoor… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder that causes progressive loss of
cognitive functions like thinking, memory, reasoning, behavioral abilities, and social skills …

[HTML][HTML] Functions and mechanisms of protein lysine butyrylation (Kbu): Therapeutic implications in human diseases

Q Xue, Y Yang, H Li, X Li, L Zou, T Li, H Ma, H Qi… - Genes & …, 2023 - Elsevier
Post-translational modifications (PTM) are covalent modifications of proteins or peptides
caused by proteolytic cleavage or the attachment of moieties to one or more amino acids …