Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis
and defence of the central nervous system (CNS). Astroglia contribute to the …

One hundred years ago, Ramón y Cajal, considered by many as the founder of modern
neuroscience, stated that neurons of the adult central nervous system (CNS) are incapable …

Abstract Objects Traumatic spinal cord injury (TSCI) causes neurological dysfunction below
the injured segment of the spinal cord, which significantly impacts the quality of life in …

Traumatic spinal cord injury (SCI) triggers a neuro-inflammatory response dominated by
tissue-resident microglia and monocyte derived macrophages (MDMs). Since activated …

Astrocytes control multiple processes in the nervous system in health and disease. It is now
clear that specific astrocyte subsets or activation states are associated with specific genomic …

Astrocytes are neural parenchymal cells that ubiquitously tile the central nervous system
(CNS). In addition to playing essential roles in healthy tissue, astrocytes exhibit an …

Central nervous system (CNS) lesions become surrounded by neuroprotective borders of
newly proliferated reactive astrocytes; however, fundamental features of these cells are …

Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial
socioeconomic implications for patients and their care-givers. Recent advances in medical …

Traumatic spinal cord injury results in severe and irreversible loss of function. The injury
triggers a complex cascade of inflammatory and pathological processes, culminating in …