Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?

B Liu, M Li, Z Zhou, X Guan, Y **ang - Journal of autoimmunity, 2020 - Elsevier
The emergent outbreak of coronavirus disease 2019 (COVID-19) has caused a global
pandemic. Acute respiratory distress syndrome (ARDS) and multiorgan dysfunction are …

Pathophysiology of chronic graft-versus-host disease and therapeutic targets

R Zeiser, BR Blazar - New England Journal of Medicine, 2017 - Mass Medical Soc
Chronic GVHD, an autoimmune disease that follows allogeneic hematopoietic-cell
transplantation, is characterized by infections and debilitating tissue injury leading to …

[HTML][HTML] The biology of chronic graft-versus-host disease: a task force report from the National Institutes of Health Consensus Development Project on Criteria for …

KR Cooke, L Luznik, S Sarantopoulos, FT Hakim… - Biology of Blood and …, 2017 - Elsevier
Chronic graft-versus-host disease (GVHD) is the leading cause of late, nonrelapse mortality
and disability in allogeneic hematopoietic cell transplantation recipients and a major …

Current concepts and advances in graft-versus-host disease immunology

GR Hill, BC Betts, V Tkachev, LS Kean… - Annual review of …, 2021 - annualreviews.org
Worldwide, each year over 30,000 patients undergo an allogeneic hema-topoietic stem cell
transplantation with the intent to cure high-risk hematologic malignancy, immunodeficiency …

Current issues in chronic graft-versus-host disease

G Socié, J Ritz - Blood, The Journal of the American Society of …, 2014 - ashpublications.org
Chronic graft-versus-host disease (GVHD) is a frequent and potentially life-threatening
complication of allogeneic hematopoietic stem cell transplantation. Increased …

Chronic graft-versus-host disease: biological insights from preclinical and clinical studies

KPA MacDonald, GR Hill… - Blood, The Journal of the …, 2017 - ashpublications.org
With the increasing use of mismatched, unrelated, and granulocyte colony-stimulating factor–
mobilized peripheral blood stem cell donor grafts and successful treatment of older …

Review of graft-versus-host disease

V Ramachandran, SS Kolli, LC Strowd - Dermatologic Clinics, 2019 - derm.theclinics.com
Methods A PubMed search was conducted using the search terms “graft versus host
disease,”“acute GVHD,”“chronic GVHD,”“pathophysiology,”“diagnosis,” and “treatment.” …

New approaches for the treatment of chronic graft-versus-host disease: current status and future directions

NEB Saidu, C Bonini, A Dickinson, M Grce… - Frontiers in …, 2020 - frontiersin.org
Chronic graft-versus-host disease (cGvHD) is a severe complication of allogeneic
hematopoietic stem cell transplantation that affects various organs leading to a reduced …

Managing high-risk CLL during transition to a new treatment era: stem cell transplantation or novel agents?

P Dreger, J Schetelig, N Andersen… - Blood, The Journal …, 2014 - ashpublications.org
Allogeneic hematopoietic stem cell transplantation (HSCT) has been considered as the
treatment of choice for patients with high-risk chronic lymphocytic leukemia (HR-CLL; ie …

GVHD prophylaxis 2020

M Gooptu, JH Antin - Frontiers in immunology, 2021 - frontiersin.org
Graft-vs. host disease (GVHD), both acute and chronic are among the chief non-relapse
complications of allogeneic transplantation which still cause substantial morbidity and …