Cellular mitophagy means that cells selectively wrap and degrade damaged mitochondria
through an autophagy mechanism, thus maintaining mitochondria and intracellular …

Obesity symbolizes a major public health problem. Overweight and obesity are associated to
the occurrence of the metabolic syndrome and to adipose tissue dysfunction. The adipose …

The emergence of OpenAI's ChatGPT has put intense spotlight on Generative AI (Gen-AI)
systems and their possible impacts on Academic integrity. This paper provides an overview …

Small molecules are pharmacological tools of considerable value for dissecting complex
biological processes and identifying potential therapeutic interventions. Recently, the …

All classic, non-surgical anticancer approaches like chemotherapy, radiotherapy or
photodynamic therapy kill cancer cells by inducing severe oxidative stress. Even tough …

Atovaquone is an FDA-approved anti-malarial drug, which first became clinically available in
the year 2000. Currently, its main usage is for the treatment of pneumocystis pneumonia …

Cancer stem cells (CSCs) are a small subpopulation of cells within a tumor that can both self‐
renew and differentiate into other cell types forming the heterogeneous tumor bulk. Since …

Mitochondria in addition to be a main cellular power station, are involved in the regulation of
many physiological processes, such as generation of reactive oxygen species, metabolite …

The potassium channel Kv1. 3 is highly expressed in the mitochondria of various cancerous
cells. Here we show that direct inhibition of Kv1. 3 using two mitochondria-targeted inhibitors …

Cancer stem cells (CSCs) are a subpopulation of tumor cells that exhibit self-renewal,
differentiation, and tumorigenicity. CSCs are highly resistant to the conventional cancer …