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Polygenic risk scores: from research tools to clinical instruments
Genome-wide association studies have shown unequivocally that common complex
disorders have a polygenic genetic architecture and have enabled researchers to identify …
disorders have a polygenic genetic architecture and have enabled researchers to identify …
Clinical utility of polygenic risk scores for coronary artery disease
D Klarin, P Natarajan - Nature Reviews Cardiology, 2022 - nature.com
Over the past decade, substantial progress has been made in the discovery of alleles
contributing to the risk of coronary artery disease. In addition to providing causal insights into …
contributing to the risk of coronary artery disease. In addition to providing causal insights into …
Genetic determinism, essentialism and reductionism: semantic clarity for contested science
KP Harden - Nature Reviews Genetics, 2023 - nature.com
Research linking genetic differences with human social and behavioural phenotypes has
long been controversial. Frequently, debates about the ethical, social and legal implications …
long been controversial. Frequently, debates about the ethical, social and legal implications …
New literacy challenge for the twenty-first century: genetic knowledge is poor even among well educated
We live in an age of rapidly advancing genetic research. This research is generating new
knowledge that has implications for personal health and well-being. The present study …
knowledge that has implications for personal health and well-being. The present study …
Teaching for genetics literacy in the post-genomic era
F Stern, K Kampourakis - Studies in Science Education, 2017 - Taylor & Francis
Research in genetics and genomics is advancing at a fast pace, and thus kee** up with
the most recent findings and conclusions can be very challenging. At the same time these …
the most recent findings and conclusions can be very challenging. At the same time these …
Defining epigenetic literacy: How to integrate epigenetics into the biology curriculum
N Gericke, B Mc Ewen - Journal of Research in Science …, 2023 - Wiley Online Library
The aim of this study is to define epigenetic literacy and describe how it can be included in
school biology. Epigenetics is a new field of research in biology with abundant societal …
school biology. Epigenetics is a new field of research in biology with abundant societal …
Exploring relationships among belief in genetic determinism, genetics knowledge, and social factors
Genetic determinism can be described as the attribution of the formation of traits to genes,
where genes are ascribed more causal power than what scientific consensus suggests …
where genes are ascribed more causal power than what scientific consensus suggests …
Potential use of clinical polygenic risk scores in psychiatry–ethical implications and communicating high polygenic risk
Psychiatric disorders present distinct clinical challenges which are partly attributable to their
multifactorial aetiology and the absence of laboratory tests that can be used to confirm …
multifactorial aetiology and the absence of laboratory tests that can be used to confirm …
Police officers, stigma, and the opioid epidemic
NE Kruis, J Choi, RH Donohue - International Journal of …, 2020 - journals.sagepub.com
Researchers have suggested that provider-based stigma of substance use disorders is one
barrier to fighting the opioid epidemic. Yet, to date, virtually no study has examined provider …
barrier to fighting the opioid epidemic. Yet, to date, virtually no study has examined provider …
Free will, determinism, and intuitive judgments about the heritability of behavior
The fact that genes and environment contribute differentially to variation in human
behaviors, traits and attitudes is central to the field of behavior genetics. Perceptions about …
behaviors, traits and attitudes is central to the field of behavior genetics. Perceptions about …