In nature, quorum sensing is one of the mechanisms bacterial populations use to
communicate with their own species or across species to coordinate behaviours. For the last …

We address the problem of regulating and kee** at a desired balance the relative
numbers between cells exhibiting a different phenotype within a monostrain microbial …

We describe two multicellular implementations of the classical P and PI feedback controllers
for the regulation of gene expression in a target cell population. Specifically, we propose to …

The control of microbes and microbial consortia to achieve specific functions requires
synthetic circuits that can reliably cope with internal and external perturbations. Circuits that …

We propose a multicellular implementation of a biomolecular PD feedback controller to
regulate gene expression in a microbial consortium. The implementation involves …

The problem of controlling cells endowed with a genetic toggle switch has been recently
highlighted as a benchmark problem in synthetic biology. It has been shown that a carefully …

This paper presents an innovative approach in synthetic biology, focusing on the
engineering of biomolecular feedback control systems within microbial consortia to achieve …

The increased complexity of synthetic microbial biocircuits highlights the need for distributed
cell functionality due to concomitant increases in metabolic and regulatory burdens imposed …

This article presents the first implementation of a proportional-integral-derivative (PID)
biomolecular controller within a consortium of different cell populations, aimed at robust …

We address the problem of controlling the dilution rate in a chemostat to regulate the ratio
between the concentrations of two microbial populations growing in continuous culture. After …