Oxidation chemistry using enzymes is approaching maturity and practical applicability in
organic synthesis. Oxidoreductases (enzymes catalysing redox reactions) enable chemists …

Peroxygenases are an emerging new class of enzymes allowing selective
oxyfunctionalisation reactions in a cofactor-independent way different from well-known P450 …

Peroxygenases offer an attractive means to address challenges in selective
oxyfunctionalization chemistry. Despite this, their application in synthetic chemistry remains …

In general, hydrogen peroxide is a stable and relatively mild oxidant and it can be regarded
as the ultimate “green” reagent because water and oxygen are the only by-products …

Lack of degradability and the accumulation of polymeric wastes increase the risk for the
health of the environment. Recently, recycling of polymeric waste materials becomes …

Enzymatic hydroxylation of activated and nonactivated sp3-carbons attracts keen interest
from the chemistry community as it is one of the most challenging tasks in organic synthesis …

Highlights•Selective oxyfunctionalizations are among the most challenging reactions in
organic synthesis.•Unspecific peroxygenases (UPO) are a diverse group of secreted fungal …

Unspecific peroxygenase (UPO) represents a new type of heme-thiolate enzyme with self-
sufficient mono (per) oxygenase activity and many potential applications in organic …

The hydroxylation of fatty acids is an appealing reaction in synthetic chemistry, although the
lack of selective catalysts hampers its industrial implementation. In this study, we have …

In 2004, the fungal heme-thiolate enzyme subfamily of unspecific peroxygenases (UPOs)
was first described in the basidiomycete Agrocybe aegerita. As UPOs naturally catalyze a …