The NLRP3 inflammasome pathway: a review of mechanisms and inhibitors for the treatment of inflammatory diseases

HM Blevins, Y Xu, S Biby, S Zhang - Frontiers in aging neuroscience, 2022 - frontiersin.org
The NLRP3 inflammasome is a multiprotein complex that plays a pivotal role in regulating
the innate immune system and inflammatory signaling. Upon activation by PAMPs and …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Saffron (Crocus sativus L.), the king of spices: An overview

L Cardone, D Castronuovo, M Perniola, N Cicco… - Scientia …, 2020 - Elsevier
Saffron is obtained from the dried red stigmas of Crocus sativus L., an autumnal herbaceous
flowering plant belonging to the Iridaceae family. It is largely cultivated in Iran, India …

Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

Curcumin supplementation and human disease: a sco** review of clinical trials

TM Panknin, CL Howe, M Hauer… - International Journal of …, 2023 - mdpi.com
Medicinal properties of turmeric (Curcuma longa L.), a plant used for centuries as an anti-
inflammatory, are attributed to its polyphenolic curcuminoids, where curcumin predominates …

Memory and brain amyloid and tau effects of a bioavailable form of curcumin in non-demented adults: a double-blind, placebo-controlled 18-month trial

GW Small, P Siddarth, Z Li, KJ Miller, L Ercoli… - The American Journal of …, 2018 - Elsevier
Objective Because curcumin's anti-inflammatory properties may protect the brain from
neurodegeneration, we studied its effect on memory in non-demented adults and explored …

[HTML][HTML] Saffron (Crocus sativus L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases

A El Midaoui, I Ghzaiel, D Vervandier-Fasseur, M Ksila… - Nutrients, 2022 - mdpi.com
Saffron (Crocus sativus L.) is a medicinal plant, originally cultivated in the East and Middle
East, and later in some Mediterranean countries. Saffron is obtained from the stigmas of the …

Is curcumin bioavailability a problem in humans: Lessons from clinical trials

AB Kunnumakkara, C Harsha, K Banik… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Since ancient times, turmeric has been used in several folklore remedies
against various ailments. The principal component of turmeric is curcumin and its efficacy …

Herbal medicines in the treatment of psychiatric disorders: 10‐year updated review

J Sarris - Phytotherapy Research, 2018 - Wiley Online Library
This paper provides a 10‐year update of the 2007 systematic review of herbal medicines
studied in a broad range of psychiatric disorders, including depression, anxiety, obsessive …

Curcumin for depression: a meta-analysis

L Fusar-Poli, L Vozza, A Gabbiadini… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is the principal curcuminoid found in turmeric (Curcuma longa), a spice frequently
used in Asian countries. Given its anti-inflammatory and antioxidant properties, it has been …