The immunology of Plasmodium vivax malaria
Plasmodium vivax infection, the predominant cause of malaria in Asia and Latin America,
affects~ 14 million individuals annually, with considerable adverse effects on wellbeing and …
affects~ 14 million individuals annually, with considerable adverse effects on wellbeing and …
Blood levels of galectin-9, an immuno-regulating molecule, reflect the severity for the acute and chronic infectious diseases
H Iwasaki-Hozumi, H Chagan-Yasutan, Y Ashino… - Biomolecules, 2021 - mdpi.com
Galectin-9 (Gal-9) is a β-galactoside-binding lectin capable of promoting or suppressing the
progression of infectious diseases. This protein is susceptible to cleavage of its linker …
progression of infectious diseases. This protein is susceptible to cleavage of its linker …
Cytotoxic CD8+ T cells recognize and kill Plasmodium vivax–infected reticulocytes
Plasmodium vivax causes approximately 100 million clinical malaria cases yearly,. The
basis of protective immunity is poorly understood and thought to be mediated by antibodies …
basis of protective immunity is poorly understood and thought to be mediated by antibodies …
Immune response pattern in recurrent Plasmodium vivax malaria
YO Chaves, AG da Costa, MLM Pereira… - Malaria journal, 2016 - Springer
Background Plasmodium vivax is the causative agent of human malaria of large geographic
distribution, with 35 million cases annually. In Brazil, it is the most prevalent species, being …
distribution, with 35 million cases annually. In Brazil, it is the most prevalent species, being …
On the cytokine/chemokine network during Plasmodium vivax malaria: new insights to understand the disease
Background The clinical outcome of malaria depends on the delicate balance between pro-
inflammatory and immunomodulatory cytokine responses triggered during infection. Despite …
inflammatory and immunomodulatory cytokine responses triggered during infection. Despite …
Plasma levels of Galectin-9 reflect disease severity in malaria infection
BPP Dembele, H Chagan-Yasutan, T Niki, Y Ashino… - Malaria Journal, 2016 - Springer
Abstract Background Galectin-9 (Gal-9) is a β-galactoside-binding lectin that interacts with
sugar moieties on glycoproteins and glycolipids of cells and pathogens. Gal-9 is known as …
sugar moieties on glycoproteins and glycolipids of cells and pathogens. Gal-9 is known as …
Association between RANTES/CCL5 levels with Plasmodium infections and malaria severity: a systematic review
Background Malaria continues to be a significant global health concern, and develo**
effective therapeutic strategies requires an understanding of the immune response to the …
effective therapeutic strategies requires an understanding of the immune response to the …
The Deubiquitinating Enzyme Cylindromatosis Dampens CD8+ T Cell Responses and Is a Critical Factor for Experimental Cerebral Malaria and Blood–Brain Barrier …
U Schmid, W Stenzel, J Koschel, M Raptaki… - Frontiers in …, 2017 - frontiersin.org
Cerebral malaria is a severe complication of human malaria and may lead to death of
Plasmodium falciparum-infected individuals. Cerebral malaria is associated with …
Plasmodium falciparum-infected individuals. Cerebral malaria is associated with …
Examining cellular immune responses to inform development of a blood-stage malaria vaccine
Naturally acquired immunity to the blood-stage of the malaria parasite develops slowly in
areas of high endemicity, but is not sterilizing. It manifests as a reduction in parasite density …
areas of high endemicity, but is not sterilizing. It manifests as a reduction in parasite density …
Comparison of leucocyte profiles between healthy children and those with asymptomatic and symptomatic Plasmodium falciparum infections
Background The immune mechanisms that determine whether a Plasmodium falciparum
infection would be symptomatic or asymptomatic are not fully understood. Several studies …
infection would be symptomatic or asymptomatic are not fully understood. Several studies …