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Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment
Decades have passed since the first nanoparticles-base medicine was approved for human
cancer treatment, and the research and development of nanoparticles for drug delivery are …
cancer treatment, and the research and development of nanoparticles for drug delivery are …
Neutrophils in chronic inflammatory diseases
A Herrero-Cervera, O Soehnlein… - Cellular & molecular …, 2022 - nature.com
Chronic inflammation is a component of many disease conditions that affect a large group of
individuals worldwide. Chronic inflammation is characterized by persistent, low-grade …
individuals worldwide. Chronic inflammation is characterized by persistent, low-grade …
Programmable probiotics modulate inflammation and gut microbiota for inflammatory bowel disease treatment after effective oral delivery
J Zhou, M Li, Q Chen, X Li, L Chen, Z Dong… - Nature …, 2022 - nature.com
Reactive oxygen species (ROS) play vital roles in intestinal inflammation. Therefore,
eliminating ROS in the inflammatory site by antioxidant enzymes such as catalase and …
eliminating ROS in the inflammatory site by antioxidant enzymes such as catalase and …
Oral administration of turmeric-derived exosome-like nanovesicles with anti-inflammatory and pro-resolving bioactions for murine colitis therapy
Background Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by
diffuse inflammation of the colonic mucosa and a relapsing and remitting course. The current …
diffuse inflammation of the colonic mucosa and a relapsing and remitting course. The current …
An engineered butyrate-derived polymer nanoplatform as a mucosa-healing enhancer potentiates the therapeutic effect of magnolol in inflammatory bowel disease
X Fan, Z Zhang, W Gao, Q Pan, K Luo, B He, Y Pu - ACS nano, 2023 - ACS Publications
Colonic epithelial damage and dysregulated immune response are crucial factors in the
progression and exacerbation of inflammatory bowel disease (IBD). Nanoenabled targeted …
progression and exacerbation of inflammatory bowel disease (IBD). Nanoenabled targeted …
Turmeric-derived nanovesicles as novel nanobiologics for targeted therapy of ulcerative colitis
C Gao, Y Zhou, Z Chen, H Li, Y **ao, W Hao… - …, 2022 - pmc.ncbi.nlm.nih.gov
Rationale: Ulcerative colitis (UC), a typical kind of inflammatory bowel disease (IBD), is an
idiopathic chronic intestinal inflammation. Conventional therapeutic strategies mainly focus …
idiopathic chronic intestinal inflammation. Conventional therapeutic strategies mainly focus …
Modified prebiotic-based “shield” armed probiotics with enhanced resistance of gastrointestinal stresses and prolonged intestinal retention for synergistic alleviation of …
Oral administration of probiotics is a promising method to alleviate inflammatory bowel
diseases (IBDs). However, gastrointestinal environmental sensitivity and inferior intestinal …
diseases (IBDs). However, gastrointestinal environmental sensitivity and inferior intestinal …
A nanoparticulate dual scavenger for targeted therapy of inflammatory bowel disease
C Shi, J Dawulieti, F Shi, C Yang, Q Qin, T Shi… - Science …, 2022 - science.org
A therapeutic strategy that targets multiple proinflammatory factors in inflammatory bowel
disease (IBD) with minimal systemic side effects would be attractive. Here, we develop a …
disease (IBD) with minimal systemic side effects would be attractive. Here, we develop a …
Harnessing polymer-derived drug delivery systems for combating inflammatory bowel disease
Y Pu, X Fan, Z Zhang, Z Guo, Q Pan, W Gao… - Journal of Controlled …, 2023 - Elsevier
The inflammatory bowel disease (IBD) is incurable, chronic, recrudescent disorders in the
inflamed intestines. Current clinic treatments are challenged by systemic exposure-induced …
inflamed intestines. Current clinic treatments are challenged by systemic exposure-induced …
Orally deliverable sequence-targeted astaxanthin nanoparticles for colitis alleviation
Y Chen, W Su, S Tie, W Cui, X Yu, L Zhang, Z Hua… - Biomaterials, 2023 - Elsevier
Orally targeted strategy of anti-inflammatory agents has attracted tremendous attention for
reducing highly health-care costs and enhancing the intervention efficiency of ulcerative …
reducing highly health-care costs and enhancing the intervention efficiency of ulcerative …