Acetylcholinesterase inhibitors from plants

PK Mukherjee, V Kumar, M Mal, PJ Houghton - Phytomedicine, 2007 - Elsevier
Inhibition of acetylcholinesterase (AChE), the key enzyme in the breakdown of acetylcholine,
is considered as a promising strategy for the treatment of neurological disorders such as …

An ecotoxicological view on neurotoxicity assessment

JB Legradi, C Di Paolo, MHS Kraak… - Environmental Sciences …, 2018 - Springer
The numbers of potential neurotoxicants in the environment are raising and pose a great risk
for humans and the environment. Currently neurotoxicity assessment is mostly performed to …

Acetylcholinesterase inhibitors from plants and fungi

PJ Houghton, Y Ren, MJ Howes - Natural product reports, 2006 - pubs.rsc.org
Covering: January 1980 to August 2005This review describes 183 compounds obtained
from plants and fungi which have been shown to inhibit acetylcholinesterase. The …

Screening for acetylcholinesterase inhibitors from Amaryllidaceae using silica gel thin-layer chromatography in combination with bioactivity staining

IK Rhee, M van de Meent, K Ingkaninan… - … of chromatography A, 2001 - Elsevier
Thin-layer chromatography (TLC) was used to screen for acetylcholinesterase inhibitors
from Amaryllidaceae extracts. The TLC plate was developed and then stained using …

Screening for acetylcholinesterase inhibitory activity in plants used in Thai traditional rejuvenating and neurotonic remedies

K Ingkaninan, P Temkitthawon, K Chuenchom… - Journal of …, 2003 - Elsevier
Acetylcholinesterase (AChE) inhibitor has been used as a drug for the symptomatic
treatment of Alzheimer's disease. In order to search for new AChE inhibitors, 32 plants used …

A rapid TLC bioautographic method for the detection of acetylcholinesterase and butyrylcholinesterase inhibitors in plants

A Marston, J Kissling… - … Analysis: An International …, 2002 - Wiley Online Library
A simple and rapid bioautographic enzyme assay on TLC plates has been developed for the
screening of acetylcholinesterase and butyrylcholinesterase inhibition by plant extracts …

Biogenic synthesis of gold nanoparticles from Terminalia arjuna bark extract: assessment of safety aspects and neuroprotective potential via antioxidant …

N Suganthy, V Sri Ramkumar, A Pugazhendhi… - … Science and Pollution …, 2018 - Springer
The development of neuroprotective drugs through eco-friendly production routes is a major
challenge for current pharmacology. The present study was carried out to synthesize gold …

An ecotoxicological approach to microplastics on terrestrial and aquatic organisms: A systematic review in assessment, monitoring and biological impact

OA Vazquez, MS Rahman - Environmental Toxicology and Pharmacology, 2021 - Elsevier
Marine and land plastic debris biodegrades at micro-and nanoscales through progressive
fragmentation. Oceanographic model studies confirm the presence of up to∼ 2.41 million …

Determination of anti-Alzheimer's disease activity of selected plant ingredients

T Tuzimski, A Petruczynik - Molecules, 2022 - mdpi.com
Neurodegenerative diseases, among which one of the more common is Alzheimer's
disease, are the one of the biggest global public health challenges facing our generation …

A unifying review of bioassay-guided fractionation, effect-directed analysis and related techniques

MG Weller - Sensors, 2012 - mdpi.com
The success of modern methods in analytical chemistry sometimes obscures the problem
that the ever increasing amount of analytical data does not necessarily give more insight of …