Neurons are often considered to be the computational engines of the brain, with synapses
acting solely as conveyers of information. But the diverse types of synaptic plasticity and the …

Studies on synaptic plasticity in the context of learning have been dominated by the view
that a single, particular type of plasticity forms the underlying mechanism for a particular type …

Neuroscience research has exploded, with more than fifty thousand neuroscientists applying
increasingly advanced methods. A mountain of new facts and mechanisms has emerged …

Synaptic connectivity varies widely across neuronal types. Cerebellar granule cells receive
five orders of magnitude fewer inputs than the Purkinje cells they innervate, and cerebellum …

The cerebellar cortex is an important system for relating neural circuits and learning. Its
promise reflects the longstanding idea that it contains simple, repeated circuit modules with …

Many microscopy studies require reconstruction from serial sections, a method of analysis
that is sometimes difficult and time‐consuming. When each section is cut, mounted and …

The function and efficacy of synaptic transmission are determined not only by the
composition and activity of pre‐and postsynaptic components but also by the environment in …

AMPA glutamate receptors (AMPARs) mediate fast excitatory synaptic transmission. Upon
fast consecutive synaptic stimulation, transmission can be depressed. Recuperation from …

Close structural and functional interactions of astrocytes with synapses play an important
role in brain function. The repertoire of ways in which astrocytes can regulate synaptic …

Neurons undergo a complex differentiation process that endows them with the ability to
generate electrical signals and to transmit them via synaptic connections. There is …