Pharmaceutical aspects of salt and cocrystal forms of APIs and characterization challenges
In recent years many efforts have been devoted to the screening and the study of new solid-
state forms of old active pharmaceutical ingredients (APIs) with salification or co …
state forms of old active pharmaceutical ingredients (APIs) with salification or co …
Towards medicinal mechanochemistry: evolution of milling from pharmaceutical solid form screening to the synthesis of active pharmaceutical ingredients (APIs)
This overview highlights the emergent area of mechanochemical reactions for making active
pharmaceutical ingredients (APIs), and covers the latest advances in the recently …
pharmaceutical ingredients (APIs), and covers the latest advances in the recently …
Creating cocrystals: A review of pharmaceutical cocrystal preparation routes and applications
Originally discovered almost a century ago, cocrystals continue to gain interest in the
modern day due to their ability to modify the physical properties of solid-state materials …
modern day due to their ability to modify the physical properties of solid-state materials …
Mechanochemistry for organic chemists: an update
We provide a brief overview of recent advances in the use of mechanochemical techniques
for the synthesis of organic molecules and materials, highlighting selected examples of …
for the synthesis of organic molecules and materials, highlighting selected examples of …
High power explosive with good sensitivity: a 2: 1 cocrystal of CL-20: HMX
O Bolton, LR Simke, PF Pagoria… - Crystal Growth & …, 2012 - ACS Publications
A novel energetic cocrystal predicted to exhibit greater power and similar sensitivity to that of
the current military standard explosive 1, 3, 5, 7-tetranitro-1, 3, 5, 7-tetrazacyclooctane …
the current military standard explosive 1, 3, 5, 7-tetranitro-1, 3, 5, 7-tetrazacyclooctane …
[HTML][HTML] A practical guide to pharmaceutical polymorph screening & selection
EH Lee - Asian Journal of Pharmaceutical Sciences, 2014 - Elsevier
Prevalence and importance of polymorphism occurring in pharmaceutical compounds are
well recognized. It is of great importance to prepare and select the right form from the …
well recognized. It is of great importance to prepare and select the right form from the …
Mechanical stimulation and solid seeding trigger single-crystal-to-single-crystal molecular domino transformations
H Ito, M Muromoto, S Kurenuma, S Ishizaka… - Nature …, 2013 - nature.com
Numerous studies have focused on the mechanical control of solid structures and phase
changes in molecular crystals. However, the molecular-level understanding of how …
changes in molecular crystals. However, the molecular-level understanding of how …
Barbituric acids as a useful tool for the construction of coordination and supramolecular compounds
In spite of its impressive record in medicinal chemistry, the role of barbituric acid H 3 BA
(pyrimidine-2, 4, 6 (1H, 3H, 5H)-trione) in coordination, organometallic and supramolecular …
(pyrimidine-2, 4, 6 (1H, 3H, 5H)-trione) in coordination, organometallic and supramolecular …
Recent advances in photofunctional polymorphs of molecular materials
B Lu, S Liu, D Yan - Chinese Chemical Letters, 2019 - Elsevier
Recently, molecule-based luminescent materials have been drawing extensive attention
due to their desirable properties and promising applications in the fields of sensors, lighting …
due to their desirable properties and promising applications in the fields of sensors, lighting …
Quantitative investigations of intermolecular interactions in 2-amino-3-nitropyridine polymorphs: Inputs from quantum mechanical calculations
Two polymorphic forms (Form–I and Form–II) of 2-amino-3-nitropyridine are structurally
characterized by single crystal X-ray diffraction analysis and compared with another …
characterized by single crystal X-ray diffraction analysis and compared with another …