Objective The literature on the mortality of depression was assessed with respect to five
issues: 1) strength of evidence for increased mortality, 2) controlling for mediating factors, 3) …

Literature and folk wisdom have long linked depression and death; however, only recently
have scientific studies examined the relation between them. Beginning in the 1970s …

Background Selected groups of patients with bipolar and unipolar disorder have an
increased mortality rate from suicide and natural causes of death. However, there has been …

OBJECTIVE: In 1970, Guze and Robins published a meta-analysis of suicide in patients with
affective illness that inferred a lifetime risk of 15%. Since then, this figure has been …

Background: All follow-up studies of causes of death in affective disordered patients have
found they have markedly elevated suicide rates and a less reproducible increased mortality …

Objectives Bipolar disorder is associated with a high risk of suicide attempts and suicide
death. The main objective of the present study was to identify and quantify the demographic …

Context Numerous studies have pointed to the failure of prophylaxis with pharmacotherapy
alone in the treat ment of bipolar I disorder. Recent investigations have demonstrated …

Objective To review and complete meta‐analysis of studies estimating standardised
mortality ratios (SMR s) in bipolar affective disorder (BPAD) for all‐cause and cause‐specific …

Objectives: To update and extend comparisons of rates of suicides and suicide attempts
among patients with major affective disorders with versus without long‐term lithium …

Objective Bipolar disorder (BD) is associated with premature mortality. All-cause and
specific mortality risks in this population remain unclear, and more studies are still needed to …