Efficient and regulated nucleocytoplasmic trafficking of macromolecules to the correct
subcellular compartment is critical for proper functions of the eukaryotic cell. The majority of …

Nuclear localization signals (NLS) are generally short peptides that act as a signal fragment
that mediates the transport of proteins from the cytoplasm into the nucleus. This NLS …

A multitude of cellular processes involve biomolecular condensates, which has led to the
suggestion that diverse pathogenic mutations may dysregulate condensates. Although proof …

Bidirectional transport of macromolecules across the nuclear envelope is a hallmark of
eukaryotic cells, in which the genetic material is compartmentalized inside the nucleus. The …

Proteins are intimately involved in executing and controlling virtually all cellular processes.
To understand the molecular mechanisms that underlie plant phenotypes, it is essential to …

The subcellular localization of proteins is critical for their functions in eukaryotic cells and is
tightly correlated with protein modifications. Here, we comprehensively investigate the …

The most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal
dementia (FTD) is a hexanucleotide repeat expansion in C9orf72 (C9-HRE). While RNA and …

Summary Arabidopsis cryptochrome 1 (CRY1) is a blue light receptor distributed in the
nucleus and cytoplasm. The nuclear CRY1, but not cytoplasmic CRY1, mediates blue light …

Plant intracellular nucleotide‐binding leucine‐rich repeat immune receptors (NLRs)
perceive the activity of pathogen‐secreted effector molecules that, when undetected …

In this paper, we present peptide-pair encoding (PPE), a general-purpose probabilistic
segmentation of protein sequences into commonly occurring variable-length sub …