The impact of the gut microbiome on extra-intestinal autoimmune diseases

E Miyauchi, C Shimokawa, A Steimle… - Nature Reviews …, 2023 - nature.com
The prevalence of autoimmune diseases (ADs) worldwide has rapidly increased over the
past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic …

Bifidobacterium mechanisms of immune modulation and tolerance

SJ Gavzy, A Kensiski, ZL Lee, EF Mongodin, B Ma… - Gut …, 2023 - Taylor & Francis
Bifidobacterium is a widely distributed commensal bacterial genus that displays beneficial
pro-homeostatic and anti-inflammatory immunomodulatory properties. Depletion or absence …

Gut microbiome and human health: Exploring how the probiotic genus Lactobacillus modulate immune responses

S Rastogi, A Singh - Frontiers in Pharmacology, 2022 - frontiersin.org
The highest density of microbes resides in human gastrointestinal tract, known as “Gut
microbiome”. Of note, the members of the genus Lactobacillus that belong to phyla …

The gut-brain axis: how microbiota and host inflammasome influence brain physiology and pathology

A Rutsch, JB Kantsjö, F Ronchi - Frontiers in immunology, 2020 - frontiersin.org
The human microbiota has a fundamental role in host physiology and pathology. Gut
microbial alteration, also known as dysbiosis, is a condition associated not only with …

Probiotics in medicine: a long debate

E Stavropoulou, E Bezirtzoglou - Frontiers in immunology, 2020 - frontiersin.org
During the last years probiotics gained the attention of clinicians for their use in the
prevention and treatment of multiple diseases. Probiotics main mechanisms of action …

Autism spectrum disorders and the gut microbiota

A Fattorusso, L Di Genova, GB Dell'Isola, E Mencaroni… - Nutrients, 2019 - mdpi.com
In recent years, there has been an emerging interest in the possible role of the gut
microbiota as a co-factor in the development of autism spectrum disorders (ASDs), as many …

Microbiome, probiotics and neurodegenerative diseases: deciphering the gut brain axis

S Westfall, N Lomis, I Kahouli, SY Dia, SP Singh… - Cellular and molecular …, 2017 - Springer
The gut microbiota is essential to health and has recently become a target for live bacterial
cell biotherapies for various chronic diseases including metabolic syndrome, diabetes …

Gut microbiota in neurodegenerative disorders

SR Sarkar, S Banerjee - Journal of neuroimmunology, 2019 - Elsevier
Gut dysbiosis, a primary factor behind various gastrointestinal disorders may also augment
lipopolysaccharides, pro-inflammatory cytokines, T helper cells and monocytes causing …

Connecting the immune system, systemic chronic inflammation and the gut microbiome: the role of sex

L Rizzetto, F Fava, KM Tuohy, C Selmi - Journal of autoimmunity, 2018 - Elsevier
Unresolved low grade systemic inflammation represents the underlying pathological
mechanism driving immune and metabolic pathways involved in autoimmune diseases …

The gut microbiota in immune-mediated inflammatory diseases

JD Forbes, G Van Domselaar… - Frontiers in microbiology, 2016 - frontiersin.org
The collection of microbes and their genes that exist within and on the human body,
collectively known as the microbiome has emerged as a principal factor in human health …