Faced with desiccation stress, many organisms deploy strategies to maintain the integrity of
their cellular components. Amorphous glassy media composed of small molecular solutes or …

Tardigrades are microscopic animals that survive desiccation by inducing biostasis. To
survive drying tardigrades rely on intrinsically disordered CAHS proteins, which also …

Many proteins do not fold into a fixed three-dimensional structure, but rather function in a
highly disordered state. These intrinsically disordered proteins pose a unique challenge to …

The tardigrade Ramazzottius varieornatus has remarkable resilience to a range of
environmental stresses. In this study, we have characterised two members of the small heat …

To survive extreme drying (anhydrobiosis), many organisms, spanning every kingdom of life,
accumulate intrinsically disordered proteins (IDPs). For decades, the ability of anhydrobiosis …

Interactions between proteins and osmolytes are ubiquitous within cells, assisting in
response to environmental stresses. However, our understanding of protein–osmolyte …

Tardigrades are known for their ability to survive extreme conditions. Reports indicate that
tardigrade thermal tolerance is enhanced in the desiccated state; however, these reports …

Desiccation, the extreme loss of water, poses a significant challenge to living organisms.
Desiccation-tolerant organisms combat this in part by accumulating desiccation tolerance …

Tardigrades, with over 1450 species, are important organisms in ecological understanding
and are valuable biological models (eg, due to their extremotolerant capabilities). While their …

Tardigrades are microscopic organisms known for their remarkable resilience to extreme
environmental conditions, including radiation and desiccation. Two key proteins, Dsup …