Diagnosis, pathophysiology, and management of cluster headache

J Hoffmann, A May - The Lancet Neurology, 2018 - thelancet.com
Cluster headache is a trigeminal autonomic cephalalgia characterised by extremely painful,
strictly unilateral, short-lasting headache attacks accompanied by ipsilateral autonomic …

Treatment of cluster headache: The American Headache Society evidence‐based guidelines

MS Robbins, AJ Starling, TM Pringsheim… - … : The Journal of …, 2016 - Wiley Online Library
Background Cluster headache (CH), the most common trigeminal autonomic cephalalgia, is
an extremely debilitating primary headache disorder that is often not optimally treated. New …

Trial of galcanezumab in prevention of episodic cluster headache

PJ Goadsby, DW Dodick, M Leone… - … England Journal of …, 2019 - Mass Medical Soc
Background Episodic cluster headache is a disabling neurologic disorder that is
characterized by daily headache attacks that occur over periods of weeks or months …

Non-invasive vagus nerve stimulation for the acute treatment of episodic and chronic cluster headache: a randomized, double-blind, sham-controlled ACT2 study

PJ Goadsby, IF de Coo, N Silver, A Tyagi… - …, 2018 - journals.sagepub.com
Background Clinical observations and results from recent studies support the use of non-
invasive vagus nerve stimulation (nVNS) for treating cluster headache (CH) attacks. This …

European Academy of Neurology guidelines on the treatment of cluster headache

A May, S Evers, PJ Goadsby, M Leone… - European Journal of …, 2023 - Wiley Online Library
Abstract Background and Purpose Cluster headache is a relatively rare, disabling primary
headache disorder with a major impact on patients' quality of life. This work presents …

Occipital nerve stimulation for the treatment of intractable chronic migraine headache: ONSTIM feasibility study

JR Saper, DW Dodick, SD Silberstein… - …, 2011 - journals.sagepub.com
Background: Medically intractable chronic migraine (CM) is a disabling illness characterized
by headache≥ 15 days per month. Methods: A multicenter, randomized, blinded, controlled …

Safety and efficacy of peripheral nerve stimulation of the occipital nerves for the management of chronic migraine: results from a randomized, multicenter, double …

SD Silberstein, DW Dodick, J Saper, B Huh… - …, 2012 - journals.sagepub.com
Background: Chronic migraine (CM) is a debilitating neurological disorder with few
treatment options. Peripheral nerve stimulation (PNS) of the occipital nerves is a potentially …

Cluster headache pathophysiology—insights from current and emerging treatments

DY Wei, PJ Goadsby - Nature Reviews Neurology, 2021 - nature.com
Cluster headache is a debilitating primary headache disorder that affects approximately
0.1% of the population worldwide. Cluster headache attacks involve severe unilateral pain …

The sphenopalatine ganglion: anatomy, pathophysiology, and therapeutic targeting in headache

MS Robbins, CE Robertson, E Kaplan… - … : The Journal of …, 2016 - Wiley Online Library
The sphenopalatine ganglion (SPG) has attracted the interest of practitioners treating head
and face pain for over a century because of its anatomical connections and role in the …

Neurobiology of migraine

PJ Goadsby, AR Charbit, AP Andreou, S Akerman… - Neuroscience, 2009 - Elsevier
Migraine is a complex disorder of the brain whose mechanisms are only now being
unraveled. It is common, disabling and economically costly. The pain suggests an important …