Advances in our understanding of the molecular mechanisms of action of cisplatin in cancer therapy

PB Tchounwou, S Dasari, FK Noubissi… - Journal of …, 2021 - Taylor & Francis
Cisplatin and other platinum-based chemotherapeutic drugs have been used extensively for
the treatment of human cancers such as bladder, blood, breast, cervical, esophageal, head …

Iron oxide nanoparticles in photothermal therapy

J Estelrich, MA Busquets - Molecules, 2018 - mdpi.com
Photothermal therapy is a kind of therapy based on increasing the temperature of tumoral
cells above 42° C. To this aim, cells must be illuminated with a laser, and the energy of the …

Engineering a HEK-293T exosome-based delivery platform for efficient tumor-targeting chemotherapy/internal irradiation combination therapy

C Wang, N Li, Y Li, S Hou, W Zhang, Z Meng… - Journal of …, 2022 - Springer
Exosomes are nanoscale monolayer membrane vesicles that are actively endogenously
secreted by mammalian cells. Currently, multifunctional exosomes with tumor-targeted …

Nanoparticulation of prodrug into medicines for cancer therapy

Y Zhang, H Cui, R Zhang, H Zhang… - Advanced …, 2021 - Wiley Online Library
This article provides a broad spectrum about the nanoprodrug fabrication advances co‐
driven by prodrug and nanotechnology development to potentiate cancer treatment. The …

Mesoporous polydopamine nanoparticles with co-delivery function for overcoming multidrug resistance via synergistic chemo-photothermal therapy

Y **ng, J Zhang, F Chen, J Liu, K Cai - Nanoscale, 2017 - pubs.rsc.org
Theranostic agents for combined chemo-photothermal therapy have attracted intensive
interest in the treatment of multi-drug resistance (MDR) in cancer therapy. However, the …

A multifunctional nano-therapeutic platform based on octahedral yolk-shell Au NR@ CuS: photothermal/photodynamic and targeted drug delivery tri-combined therapy …

R Huang, C Zhang, Y Bu, Z Li, X Zheng, S Qiu… - Biomaterials, 2021 - Elsevier
Rheumatoid arthritis (RA) is a common chronic autoimmune disease that results from
synovial hyperplasia. The hyperplasia of synovium directly degrades cartilage by secreting …

Recent updates in nanoscale delivery systems of platinum (IV) antitumor prodrugs

Z Zhou, P Shi, C Wang, Y Sun, C Gao - Coordination Chemistry Reviews, 2024 - Elsevier
Platinum-based anticancer drugs still play a crucial role in the treatment of various solid
tumors such as ovarian, lung, colorectal, bladder, and breast cancer. However, their ability to …

Novel delivery approaches for cancer therapeutics

AK Mitra, V Agrahari, A Mandal, K Cholkar… - Journal of controlled …, 2015 - Elsevier
Currently, a majority of cancer treatment strategies are based on the removal of tumor mass
mainly by surgery. Chemical and physical treatments such as chemo-and radiotherapies …

Biomedical, clinical and environmental applications of platinum-based nanohybrids: An updated review

ST Yerpude, AK Potbhare, P Bhilkar, AR Rai… - Environmental …, 2023 - Elsevier
Abstract Platinum nanoparticles (Pt NPs) have numerous applications in various sectors,
including pharmacology, nanomedicine, cancer therapy, radiotherapy, biotechnology and …

Emerging platinum (IV) prodrug nanotherapeutics: A new epoch for platinum-based cancer therapy

S Zheng, G Li, J Shi, X Liu, M Li, Z He, C Tian… - Journal of Controlled …, 2023 - Elsevier
Owing to the unique DNA damaging cytotoxicity, platinum (Pt)-based chemotherapy has
long been the first-line choice for clinical oncology. Unfortunately, Pt drugs are restricted by …