In recent years, tumor immunotherapy has made significant progress. However, tumor
immunotherapy, particularly immune checkpoint inhibitors (eg, PD-1/PD-L1 inhibitors) …

Strategies to therapeutically target the tumor microenvironment (TME) have emerged as a
promising approach for cancer treatment in recent years due to the critical roles of the TME …

CC chemokines, a subfamily of 27 chemotactic cytokines, are a component of intercellular
communication, which is crucial for the functioning of the tumor microenvironment. Although …

The potential roles of breast cancer stem cells (BCSCs) in tumor initiation and recurrence
have been recognized for many decades. Due to their strong capacity for self-renewal and …

Infiltration of macrophages in solid tumours is associated with poor prognosis and correlates
with chemotherapy resistance in most cancers. In mouse models of cancer, macrophages …

The communication between cells and their microenvironment represents an intrinsic and
essential attribute that takes place in several biological processes, including tissue …

Cell-penetrating-peptides (CPPs) are small amino-acid sequences characterized by their
ability to cross cellular membranes. They can transport various bioactive cargos inside cells …

Triple-negative breast cancer (TNBC) is associated with a poor prognosis, due to its
aggressive behaviour and lack of effective targeted therapies. Immunocheckpoint inhibitors …

It is well known that the microenvironment of solid tumors is rich in inflammatory cells that
influence tumor growth and development. Macrophages, called tumor-associated …

The tumor microenvironment (TME) plays key roles in promoting disease progression in the
aggressive triple-negative subtype of breast cancer (TNBC; Basal/Basal-like). Here, we took …