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Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …
the development of mesoporous materials, their different synthetic routes and their use as …
Recent progress in the applications of silica-based nanoparticles
Functionalized silica nanoparticles (SiO2 NPs) have attracted great attention due to their
promising distinctive, versatile, and privileged physiochemical characteristics. These …
promising distinctive, versatile, and privileged physiochemical characteristics. These …
[HTML][HTML] In vivo delivery of CRISPR-Cas9 therapeutics: Progress and challenges
Within less than a decade since its inception, CRISPR-Cas9-based genome editing has
been rapidly advanced to human clinical trials in multiple disease areas. Although it is highly …
been rapidly advanced to human clinical trials in multiple disease areas. Although it is highly …
Silicon-containing nanomedicine and biomaterials: materials chemistry, multi-dimensional design, and biomedical application
L Chen, S Zhang, Y Duan, X Song, M Chang… - Chemical Society …, 2024 - pubs.rsc.org
The invention of silica-based bioactive glass in the late 1960s has sparked significant
interest in exploring a wide range of silicon-containing biomaterials from the macroscale to …
interest in exploring a wide range of silicon-containing biomaterials from the macroscale to …
Non-viral delivery of the CRISPR/Cas system: DNA versus RNA versus RNP
Since its discovery, the CRISPR/Cas technology has rapidly become an essential tool in
modern biomedical research. The opportunities to specifically modify and correct genomic …
modern biomedical research. The opportunities to specifically modify and correct genomic …
Future of mesoporous silica nanoparticles in nanomedicine: protocol for reproducible synthesis, characterization, lipid coating, and loading of therapeutics …
A Noureddine, A Maestas-Olguin, L Tang… - 2023 - ACS Publications
Owing to their uniform and tunable particle size, pore size, and shape, along with their
modular surface chemistry and biocompatibility, mesoporous silica nanoparticles (MSNs) …
modular surface chemistry and biocompatibility, mesoporous silica nanoparticles (MSNs) …
Recent advances of metal-based nanoparticles in nucleic acid delivery for therapeutic applications
AR Sharma, YH Lee, A Bat-Ulzii… - Journal of …, 2022 - Springer
Recent efforts in designing nanomaterials to deliver potential therapeutics to the targeted
site are overwhelming and palpable. Engineering nanomaterials to deliver biological …
site are overwhelming and palpable. Engineering nanomaterials to deliver biological …
Polymeric micellar nanoparticles for effective CRISPR/Cas9 genome editing in cancer
Y Li, C Li, J Yan, Y Liao, C Qin, L Wang, Y Huang… - Biomaterials, 2024 - Elsevier
The clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein 9
(Cas9) gene editing has attracted extensive attentions in various fields, however, its clinical …
(Cas9) gene editing has attracted extensive attentions in various fields, however, its clinical …
Carrier strategies boost the application of CRISPR/Cas system in gene therapy
Z Xu, Q Wang, H Zhong, Y Jiang, X Shi, B Yuan… - …, 2022 - Wiley Online Library
Emerging clustered regularly interspaced short palindromic repeat/associated protein
(CRISPR/Cas) genome editing technology shows great potential in gene therapy. However …
(CRISPR/Cas) genome editing technology shows great potential in gene therapy. However …
[HTML][HTML] An update on mesoporous silica nanoparticle applications in nanomedicine
The efficient and safe delivery of therapeutic drugs, proteins, and nucleic acids are essential
for meaningful therapeutic benefits. The field of nanomedicine shows promising implications …
for meaningful therapeutic benefits. The field of nanomedicine shows promising implications …