Extracellular vesicles (EVs) are lipid bilayer membrane particles that play critical roles in
intracellular communication through EV-encapsulated informative content, including …

Hematopoietic stem cells (HSCs) are the life-long source of all types of blood cells. Their
function is controlled by their direct microenvironment, the HSC niche in the bone marrow …

As major complications of chemoradiotherapy, myelosuppression and hematopoietic‐
system damage severely affect immunologic function and can delay or even terminate …

The relevance of cellular in vitro models highly depends on their ability to mimic the
physiological environment of the respective tissue or cell niche. Static culture conditions are …

Hematopoietic stem cell (HSC) transplantation remains the most effective therapy for
hematologic and lymphoid disorders. However, as the primary therapeutic cells, the source …

Haematopoietic stem cells are the basis for building and maintaining lifelong
haematopoietic mechanisms and an important resource for the treatment of blood disorders …

The journey of a hematopoietic stem cell (HSC) involves the passage through successive
anatomical sites where HSCs are in direct contact with their surrounding microenvironment …

Hematopoietic stem cells are the progenitors of the blood and immune system and represent
the most widely used regenerative therapy. However, their rarity and limited donor base …

Hematopoietic stem cell (HSC) expansion offers a key strategy to address the source
limitation and donor shortages of HSCs for the treatment of various blood disorders. Specific …

Hematopoietic stem cells (HSCs) are an ideal source for the treatment of many
hematological diseases and malignancies, as well as diseases of other systems, because of …