[HTML][HTML] Management of Epstein-Barr Virus infections and post-transplant lymphoproliferative disorders in patients after allogeneic hematopoietic stem cell …
J Styczynski, W van der Velden, CP Fox… - …, 2016 - ncbi.nlm.nih.gov
Epstein-Barr virus-related post-transplant lymphoproliferative disorders are recognized as a
significant cause of morbidity and mortality in patients undergoing hematopoietic stem cell …
significant cause of morbidity and mortality in patients undergoing hematopoietic stem cell …
Hematopoietic stem cell transplantation in its 60s: a platform for cellular therapies
Over the last 60 years, more than a million patients received hematopoietic cell
transplantation. Having incorporated multiple changes in clinical practices, it remains a …
transplantation. Having incorporated multiple changes in clinical practices, it remains a …
Off-the-shelf EBV-specific T cell immunotherapy for rituximab-refractory EBV-associated lymphoma following transplantation
S Prockop, E Doubrovina, S Suser… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Adoptive transfer of donor-derived EBV-specific cytotoxic T-lymphocytes
(EBV-CTLs) can eradicate EBV-associated lymphomas (EBV-PTLD) after transplantation of …
(EBV-CTLs) can eradicate EBV-associated lymphomas (EBV-PTLD) after transplantation of …
A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of …
H Torikai, A Reik, PQ Liu, Y Zhou… - Blood, The Journal …, 2012 - ashpublications.org
Clinical-grade T cells are genetically modified ex vivo to express a chimeric antigen receptor
(CAR) to redirect specificity to a tumor associated antigen (TAA) thereby conferring antitumor …
(CAR) to redirect specificity to a tumor associated antigen (TAA) thereby conferring antitumor …
Activity of broad-spectrum T cells as treatment for AdV, EBV, CMV, BKV, and HHV6 infections after HSCT
It remains difficult to treat the multiplicity of distinct viral infections that afflict
immunocompromised patients. Adoptive transfer of virus-specific T cells (VSTs) can be safe …
immunocompromised patients. Adoptive transfer of virus-specific T cells (VSTs) can be safe …
Adoptive immunotherapy with unselected or EBV-specific T cells for biopsy-proven EBV+ lymphomas after allogeneic hematopoietic cell transplantation
E Doubrovina, B Oflaz-Sozmen… - Blood, The Journal …, 2012 - ashpublications.org
We evaluated HLA-compatible donor leukocyte infusions (DLIs) and HLA-compatible or HLA-
disparate EBV-specific T cells (EBV-CTLs) in 49 hematopoietic cell transplantation …
disparate EBV-specific T cells (EBV-CTLs) in 49 hematopoietic cell transplantation …
Adoptive immunotherapy for cancer or viruses
Adoptive immunotherapy, or the infusion of lymphocytes, is a promising approach for the
treatment of cancer and certain chronic viral infections. The application of the principles of …
treatment of cancer and certain chronic viral infections. The application of the principles of …
T cells for viral infections after allogeneic hematopoietic stem cell transplant
Despite recent advances in the field of allogeneic hematopoietic stem cell transplantation
(HSCT), viral infections are still a major complication during the period of immune …
(HSCT), viral infections are still a major complication during the period of immune …
Transfer of minimally manipulated CMV-specific T cells from stem cell or third-party donors to treat CMV infection after allo-HSCT
M Neuenhahn, J Albrecht, M Odendahl, F Schlott… - Leukemia, 2017 - nature.com
Cytomegalovirus (CMV) infection is a common, potentially life-threatening complication
following allogeneic hematopoietic stem cell transplantation (allo-HSCT). We assessed …
following allogeneic hematopoietic stem cell transplantation (allo-HSCT). We assessed …
Response to rituximab-based therapy and risk factor analysis in Epstein Barr virus–related lymphoproliferative disorder after hematopoietic stem cell transplant in …
J Styczynski, L Gil, G Tridello… - Clinical infectious …, 2013 - academic.oup.com
Background. The objective of this analysis was to investigate prognostic factors that
influence the outcome of Epstein-Barr virus (EBV)–related posttransplant lymphoproliferative …
influence the outcome of Epstein-Barr virus (EBV)–related posttransplant lymphoproliferative …