[HTML][HTML] Quantitative imaging for radiotherapy purposes

OJ Gurney-Champion, F Mahmood, M van Schie… - Radiotherapy and …, 2020 - Elsevier
Quantitative imaging biomarkers show great potential for use in radiotherapy. Quantitative
images based on microscopic tissue properties and tissue function can be used to improve …

Deep learning how to fit an intravoxel incoherent motion model to diffusion‐weighted MRI

S Barbieri, OJ Gurney‐Champion… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose This prospective clinical study assesses the feasibility of training a deep neural
network (DNN) for intravoxel incoherent motion (IVIM) model fitting to diffusion‐weighted …

Novel strategies using modern radiotherapy to improve pancreatic cancer outcomes: toward a new standard?

C Bouchart, J Navez, J Closset… - … in medical oncology, 2020 - journals.sagepub.com
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive solid
tumours with an estimated 5-year overall survival rate of 7% for all stages combined. In this …

Improved unsupervised physics‐informed deep learning for intravoxel incoherent motion modeling and evaluation in pancreatic cancer patients

MPT Kaandorp, S Barbieri, R Klaassen… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose Earlier work showed that IVIM‐NETorig, an unsupervised physics‐informed deep
neural network, was faster and more accurate than other state‐of‐the‐art intravoxel …

Assessment of imaging modalities against liver biopsy in nonalcoholic fatty liver disease: The Amsterdam NAFLD‐NASH cohort

MA Troelstra, JJ Witjes, AM van Dijk… - Journal of Magnetic …, 2021 - Wiley Online Library
Background Noninvasive diagnostic methods are urgently required in disease stratification
and monitoring in nonalcoholic fatty liver disease (NAFLD). Multiparametric magnetic …

Pathological validation and prognostic potential of quantitative MRI in the characterization of pancreas cancer: preliminary experience

R Klaassen, A Steins, OJ Gurney‐Champion… - Molecular …, 2020 - Wiley Online Library
Patient stratification based on biological variation in pancreatic ductal adenocarcinoma
(PDAC) subtypes could help to improve clinical outcome. However, noninvasive assessment …

Assessment of tissue perfusion of pancreatic cancer as potential imaging biomarker by means of Intravoxel incoherent motion MRI and CT perfusion: correlation with …

P Mayer, F Fritz, M Koell, S Skornitzke, F Bergmann… - Cancer Imaging, 2021 - Springer
Background/objectives The aim of this study was to compare intravoxel incoherent motion
(IVIM) diffusion weighted (DW) MRI and CT perfusion to assess tumor perfusion of …

Evaluation of Monoexponential, Stretched‐Exponential and Intravoxel Incoherent Motion MRI Diffusion Models in Early Response Monitoring to Neoadjuvant …

ZM Almutlaq, DJ Wilson, SE Bacon… - Journal of Magnetic …, 2022 - Wiley Online Library
Background There has been a growing interest in exploring the applications of stretched‐
exponential (SEM) and intravoxel incoherent motion (IVIM) models of diffusion‐weighted …

Multi‐parametric MRI (mpMRI) for treatment response assessment of radiation therapy

C Wang, KR Padgett, MY Su, EA Mellon… - Medical …, 2022 - Wiley Online Library
Magnetic resonance imaging (MRI) plays an important role in the modern radiation therapy
(RT) workflow. In comparison with computed tomography (CT) imaging, which is the …

Principal component analysis for fast and model-free denoising of multi b-value diffusion-weighted MR images

OJ Gurney-Champion, DJ Collins… - Physics in Medicine …, 2019 - iopscience.iop.org
Despite the utility of tumour characterisation using quantitative parameter maps from multi-b-
value diffusion-weighted MRI (DWI), clinicians often prefer the use of the image with highest …