[HTML][HTML] The pathophysiology of Parkinson's disease tremor

MF Dirkx, M Bologna - Journal of the Neurological Sciences, 2022 - Elsevier
Tremor is one of the primary motor symptoms of Parkinson's disease (PD), and it is
characterized by a highly phenomenological heterogeneity. Clinical and experimental …

A review on pathology, mechanism, and therapy for cerebellum and tremor in Parkinson's disease

Y Zhong, H Liu, G Liu, L Zhao, C Dai, Y Liang… - npj Parkinson's …, 2022 - nature.com
Tremor is one of the core symptoms of Parkinson's disease (PD), but its mechanism is poorly
understood. The cerebellum is a growing focus in PD-related researches and is reported to …

[HTML][HTML] Clinical neurophysiology of Parkinson's disease and parkinsonism

R Chen, A Berardelli, A Bhattacharya… - Clinical neurophysiology …, 2022 - Elsevier
This review is part of the series on the clinical neurophysiology of movement disorders. It
focuses on Parkinson's disease and parkinsonism. The topics covered include the …

Clinical severity in Parkinson's disease is determined by decline in cortical compensation

ME Johansson, I Toni, RPC Kessels, BR Bloem… - Brain, 2024 - academic.oup.com
Dopaminergic dysfunction in the basal ganglia, particularly in the posterior putamen, is often
viewed as the primary pathological mechanism behind motor slowing (ie bradykinesia) in …

[HTML][HTML] The clinical and electrophysiological investigation of tremor

G Deuschl, JS Becktepe, M Dirkx… - Clinical …, 2022 - Elsevier
The various forms of tremor are now classified in two axes: clinical characteristics (axis 1)
and etiology (axis 2). Electrophysiology is an extension of the clinical exam …

Stress and mindfulness in Parkinson's disease: clinical effects and potential underlying mechanisms

A Van der Heide, MJ Meinders… - Movement …, 2021 - Wiley Online Library
Patients with Parkinson's disease (PD) are very vulnerable to the negative effects of
psychological distress: neuropsychiatric symptoms, such as anxiety and depression, are …

Stress and mindfulness in Parkinson's disease–a survey in 5000 patients

A van der Heide, AEM Speckens, MJ Meinders… - npj Parkinson's …, 2021 - nature.com
Many Parkinson's disease (PD) patients notice that motor symptoms worsen during stress,
and experience stress-related neuropsychiatric symptoms such as anxiety and depression …

Relative sparing of dopaminergic terminals in the caudate nucleus is a feature of rest tremor in Parkinson's disease

MD Mendonça, PC Ferreira, F Oliveira… - npj Parkinson's …, 2024 - nature.com
Resting tremor (RT) is a Parkinson's disease (PD) symptom with an unclear relationship to
the dopaminergic system. We analysed data from 432 subjects from the Parkinson's …

Machine Learning in the Parkinson's disease smartwatch (PADS) dataset

J Varghese, A Brenner, M Fujarski, CM van Alen… - npj Parkinson's …, 2024 - nature.com
The utilisation of smart devices, such as smartwatches and smartphones, in the field of
movement disorders research has gained significant attention. However, the absence of a …

Machine learning in tremor analysis: critique and directions

A De, KP Bhatia, J Volkmann, R Peach… - Movement …, 2023 - Wiley Online Library
Tremor is the most frequent human movement disorder, and its diagnosis is based on
clinical assessment. Yet finding the accurate clinical diagnosis is not always straightforward …