The donepezil transdermal system for the treatment of patients with mild, moderate, or severe Alzheimer's disease: A critical review

A Buck, K Rezaei, A Quazi, G Goldmeier… - Expert Review of …, 2024 - Taylor & Francis
Introduction Cholinesterase inhibitors, along with memantine, are the mainstay of
symptomatic treatment for AD (Alzheimer's disease); however, these medications are …

Exopolysaccharide and biopolymer-derived films as tools for transdermal drug delivery

J Laubach, M Joseph, T Brenza… - Journal of controlled …, 2021 - Elsevier
Microbial exopolysaccharides (EPSs) exhibit diverse functionalities and offer a variety of
structural options that can be altered to fit a specific purpose. EPSs can degrade within the …

Pectin-based silver nanocomposite film for transdermal delivery of Donepezil

AK Kodoth, VM Ghate, SA Lewis, B Prakash… - International journal of …, 2019 - Elsevier
A novel pectin-based silver nanocomposite film has been synthesized with the aid of
microwave, using green technology and its capacity to adsorb and deliver anti-Alzheimer's …

Electrically controlled drug release of donepezil and BiFeO3 magnetic nanoparticle-loaded PVA microbubbles/nanoparticles for the treatment of Alzheimer's disease

S Cesur, ME Cam, FS Sayin, O Gunduz - Journal of Drug Delivery Science …, 2022 - Elsevier
Nanocarriers are used to deliver bioactive substances in the treatment of neurodegenerative
diseases such as Alzheimer's disease (AD). These nanocarriers have shown many benefits …

Polyurethane/hydroxypropyl cellulose electrospun nanofiber mats as potential transdermal drug delivery system: characterization studies and in vitro assays

A Gencturk, E Kahraman, S Güngör… - Artificial cells …, 2017 - Taylor & Francis
Donepezil hydrochloride containing polyurethane/hydroxypropyl cellulose (PU/HPC)
nanofibers were prepared by the electrospinning for transdermal drug delivery. PU/HPC …

Recent update on alginate based promising transdermal drug delivery systems

S Manna, P Gupta, G Nandi, S Jana - Journal of Biomaterials …, 2023 - Taylor & Francis
Alongside oral delivery of therapeutics, transdermal delivery systems have gained increased
patient acceptability over past few decades. With increasing popularity, novel techniques …

Donepezil—An updated review of challenges in dosage form design

L Sutthapitaksakul, CR Dass, P Sriamornsak - Journal of Drug Delivery …, 2021 - Elsevier
Donepezil hydrochloride (DPH) was first launched in 1997 as a choline esterase inhibitor
(ChEI). The USFDA has approved it for treatment of Alzheimer's disease since it effectively …

Current advances in transdermal delivery of drugs for Alzheimer's disease

TT Nguyen, V Van Giau, TK Vo - Indian journal of pharmacology, 2017 - journals.lww.com
Alzheimer's disease (AD) is a common, progressive, fatal neurodegenerative disorder,
which will play an increasingly important role both socially and financially in the aging …

Preparation, characterization, and in vivo pharmacokinetic evaluation of polyvinyl alcohol and polyvinyl pyrrolidone blended hydrogels for transdermal delivery of …

S Bashyal, CY Shin, SM Hyun, SW Jang, S Lee - Pharmaceutics, 2020 - mdpi.com
Transdermal delivery systems are emerging platforms for the delivery of donepezil
hydrochloride (DH) for treating Alzheimer's disease. The primary aim of this study was to …

Applications of polysaccharides in topical and transdermal drug delivery: A recent update of literature

R Parhi, SK Sahoo, A Das - Brazilian Journal of Pharmaceutical …, 2022 - SciELO Brasil
The main aim of transdermal drug delivery (TDD) is to deliver a specific dose of drug across
the skin and to reach systemic circulation at a controlled rate. On the other hand skin is the …