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T cell responses to SARS-CoV-2
A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
[HTML][HTML] SARS-CoV-2 Omicron variant: recent progress and future perspectives
Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, there have been
a few variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), one of …
a few variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), one of …
SARS-CoV-2 pathogenesis
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …
Dictionary learning for integrative, multimodal and scalable single-cell analysis
Map** single-cell sequencing profiles to comprehensive reference datasets provides a
powerful alternative to unsupervised analysis. However, most reference datasets are …
powerful alternative to unsupervised analysis. However, most reference datasets are …
[HTML][HTML] Systems vaccinology of the BNT162b2 mRNA vaccine in humans
The emergency use authorization of two mRNA vaccines in less than a year from the
emergence of SARS-CoV-2 represents a landmark in vaccinology,. Yet, how mRNA …
emergence of SARS-CoV-2 represents a landmark in vaccinology,. Yet, how mRNA …
Chronic inflammation, neutrophil activity, and autoreactivity splits long COVID
While immunologic correlates of COVID-19 have been widely reported, their associations
with post-acute sequelae of COVID-19 (PASC) remain less clear. Due to the wide array of …
with post-acute sequelae of COVID-19 (PASC) remain less clear. Due to the wide array of …
Single-cell multi-omics analysis of the immune response in COVID-19
Abstract Analysis of human blood immune cells provides insights into the coordinated
response to viral infections such as severe acute respiratory syndrome coronavirus 2, which …
response to viral infections such as severe acute respiratory syndrome coronavirus 2, which …
Host-directed immunotherapy of viral and bacterial infections: past, present and future
The advent of COVID-19 and the persistent threat of infectious diseases such as
tuberculosis, malaria, influenza and HIV/AIDS remind us of the marked impact that infections …
tuberculosis, malaria, influenza and HIV/AIDS remind us of the marked impact that infections …
A Python library for probabilistic analysis of single-cell omics data
To the Editor—Methods for analyzing single-cell data 1–4 perform a core set of
computational tasks. These tasks include dimensionality reduction, cell clustering, cell-state …
computational tasks. These tasks include dimensionality reduction, cell clustering, cell-state …
[HTML][HTML] Adaptive immunity to SARS-CoV-2 and COVID-19
The adaptive immune system is important for control of most viral infections. The three
fundamental components of the adaptive immune system are B cells (the source of …
fundamental components of the adaptive immune system are B cells (the source of …