Immunosuppressive tumor microenvironment in the progression, metastasis, and therapy of hepatocellular carcinoma: from bench to bedside
Y Yin, W Feng, J Chen, X Chen, G Wang… - … hematology & oncology, 2024 - Springer
Hepatocellular carcinoma (HCC) is a highly heterogeneous malignancy with high incidence,
recurrence, and metastasis rates. The emergence of immunotherapy has improved the …
recurrence, and metastasis rates. The emergence of immunotherapy has improved the …
Role of cell division cycle-associated proteins in regulating cell cycle and promoting tumor progression
Z Wang, M Ren, W Liu, J Wu, P Tang - Biochimica et Biophysica Acta (BBA) …, 2024 - Elsevier
The cell division cycle-associated protein (CDCA) family is important in regulating cell
division. High CDCA expression is significantly linked to tumor development. This review …
division. High CDCA expression is significantly linked to tumor development. This review …
Myeloid-like tumor hybrid cells in bone marrow promote progression of prostate cancer bone metastasis
X Ye, X Huang, X Fu, X Zhang, R Lin, W Zhang… - Journal of Hematology & …, 2023 - Springer
Background Bone metastasis is the leading cause of death in patients with prostate cancer
(PCa) and currently has no effective treatment. Disseminated tumor cells in bone marrow …
(PCa) and currently has no effective treatment. Disseminated tumor cells in bone marrow …
[HTML][HTML] CDCA8, a mitosis-related gene, as a prospective pan-cancer biomarker: implications for survival prognosis and oncogenic immunology
Background: Human cell division cycle-associated protein 8 (CDCA8), a critical regulator of
mitosis, has been identified as a prospective prognostic biomarker in several cancer types …
mitosis, has been identified as a prospective prognostic biomarker in several cancer types …
Interaction of STIL with FOXM1 regulates SF3A3 transcription in the hepatocellular carcinoma development
H Zhang, L Zhang, Z Wu - Cell Division, 2025 - Springer
Background Dysregulation of SF3A3 has been related to the development of many cancers.
Here, we investigated the functional role of SF3A3 in hepatocellular carcinoma (HCC) …
Here, we investigated the functional role of SF3A3 in hepatocellular carcinoma (HCC) …
Expression and Purification of Recombinant Bowman–Birk Trypsin Inhibitor from Foxtail Millet Bran and Its Anticolorectal Cancer Effect In Vitro and In Vivo
H Zhang, Q Qiao, Y Zhao, L Zhang, J Shi… - Journal of Agricultural …, 2024 - ACS Publications
Trypsin inhibitors derived from plants have various pharmacological activities and promising
clinical applications. In our previous study, a Bowman–Birk-type major trypsin inhibitor from …
clinical applications. In our previous study, a Bowman–Birk-type major trypsin inhibitor from …
Targeting nerve growth factor-mediated osteosarcoma metastasis: mechanistic insights and therapeutic opportunities using larotrectinib
CH Hou, WL Chen, CY Lin - Cell Death & Disease, 2024 - nature.com
Osteosarcoma (OS) therapy presents numerous challenges, due largely to a low survival
rate following metastasis onset. Nerve growth factor (NGF) has been implicated in the …
rate following metastasis onset. Nerve growth factor (NGF) has been implicated in the …
[HTML][HTML] Expression and function of NF-Y subunits in cancer
NF-Y is a Transcription Factor-TF-targeting the CCAAT box regulatory element. It consists of
the NF-YB/NF-YC heterodimer, each containing an Histone Fold Domain-HFD-and the …
the NF-YB/NF-YC heterodimer, each containing an Histone Fold Domain-HFD-and the …
A hypoxia–glycolysis–lactate-related gene signature for prognosis prediction in hepatocellular carcinoma
X Qin, H Sun, S Hu, Y Pan, S Wang - BMC Medical Genomics, 2024 - Springer
Background Liver cancer ranks sixth in incidence and third in mortality globally and
hepatocellular carcinoma (HCC) accounts for 90% of it. Hypoxia, glycolysis, and lactate …
hepatocellular carcinoma (HCC) accounts for 90% of it. Hypoxia, glycolysis, and lactate …
ZMIZ2 facilitates hepatocellular carcinoma progression via LEF1 mediated activation of Wnt/β-catenin pathway
Y Ding, Y Ning, H Kang, Y Yuan, K Lin, C Wang… - … Hematology & Oncology, 2024 - Springer
Background Hepatocellular carcinoma (HCC) is one of the most common malignancies with
a high lethality rate. ZMIZ2 is a transcriptional co-activator implicated in various human …
a high lethality rate. ZMIZ2 is a transcriptional co-activator implicated in various human …