Glioblastoma multiforme (GBM): An overview of current therapies and mechanisms of resistance

W Wu, JL Klockow, M Zhang, F Lafortune… - Pharmacological …, 2021 - Elsevier
Glioblastoma multiforme (GBM) is a WHO grade IV glioma and the most common malignant,
primary brain tumor with a 5-year survival of 7.2%. Its highly infiltrative nature, genetic …

Management of glioblastoma: State of the art and future directions

AC Tan, DM Ashley, GY López… - CA: a cancer journal …, 2020 - Wiley Online Library
Glioblastoma is the most common malignant primary brain tumor. Overall, the prognosis for
patients with this disease is poor, with a median survival of< 2 years. There is a slight …

Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future …

PY Wen, M Weller, EQ Lee, BM Alexander… - Neuro …, 2020 - academic.oup.com
Glioblastomas are the most common form of malignant primary brain tumor and an important
cause of morbidity and mortality. In recent years there have been important advances in …

Glioblastoma therapy: Past, present and future

E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

Liquid exfoliation of ultrasmall zirconium carbide nanodots as a noninflammatory photothermal agent in the treatment of glioma

D Liu, X Dai, W Zhang, X Zhu, Z Zha, H Qian, L Cheng… - Biomaterials, 2023 - Elsevier
Photothermal therapy (PTT), like other clinical translational tumor ablation techniques,
requires a temperature increase above 50° C to cause necrosis and death of tumor cells …

Nanosensitizers for sonodynamic therapy for glioblastoma multiforme: current progress and future perspectives

QL Guo, XL Dai, MY Yin, HW Cheng, HS Qian… - Military Medical …, 2022 - Springer
Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor, and it is
associated with poor prognosis. Its characteristics of being highly invasive and undergoing …

Signaling pathways and therapeutic approaches in glioblastoma multiforme

M Khabibov, A Garifullin… - International …, 2022 - spandidos-publications.com
Glioblastoma multiforme (GBM) is the most aggressive type of primary brain tumor and is
associated with a poor clinical prognosis. Despite the progress in the understanding of the …

Recurrent glioblastoma: from molecular landscape to new treatment perspectives

C Birzu, P French, M Caccese, G Cerretti, A Idbaih… - Cancers, 2020 - mdpi.com
Simple Summary Glioblastoma is the most common and aggressive malignant primary brain
cancer in adults. The prognosis remains poor following standard-of-care treatment with …

Current standards of care in glioblastoma therapy

C Fernandes, A Costa, L Osório, RC Lago… - Exon …, 2017 - exonpublications.com
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults.
Regardless of ideal multidisciplinary treatment, including maximal surgical resection …

Complete resection of contrast-enhancing tumor volume is associated with improved survival in recurrent glioblastoma—results from the DIRECTOR trial

B Suchorska, M Weller, G Tabatabai, C Senft… - Neuro …, 2016 - academic.oup.com
Background The role of reoperation for recurrent glioblastoma (GBM) remains unclear.
Prospective studies are lacking. Here, we studied the association of clinical outcome with …