The diagnosis and management of mild cognitive impairment: a clinical review

KM Langa, DA Levine - Jama, 2014 - jamanetwork.com
Importance Cognitive decline is a common and feared aspect of aging. Mild cognitive
impairment (MCI) is defined as the symptomatic predementia stage on the continuum of …

Practical recommendations for timely, accurate diagnosis of symptomatic Alzheimer's disease (MCI and dementia) in primary care: a review and synthesis

JL Liss, S Seleri Assunção, J Cummings… - Journal of internal …, 2021 - Wiley Online Library
The critical role of primary care clinicians (PCCs) in Alzheimer's disease (AD) prevention,
diagnosis and management must evolve as new treatment paradigms and disease …

Neuroinflammation: a potential risk for dementia

MA Ahmad, O Kareem, M Khushtar, M Akbar… - International journal of …, 2022 - mdpi.com
Dementia is a neurodegenerative condition that is considered a major factor contributing to
cognitive decline that reduces independent function. Pathophysiological pathways are not …

Risk of conversion from mild cognitive impairment to dementia in low‐and middle‐income countries: a systematic review and meta‐analysis

AM McGrattan, E Pakpahan, M Siervo… - … Research & Clinical …, 2022 - Wiley Online Library
Introduction With no treatment for dementia, there is a need to identify high risk cases to
focus preventive strategies, particularly in low‐and middle‐income countries (LMICs) where …

Cognition and gait in older people

JA Cohen, J Verghese, JL Zwerling - Maturitas, 2016 - Elsevier
Cognitive difficulties and gait abnormalities both increase with age. We review normal and
pathologic changes in both gait and cognition in older adults. Gait performance in older …

Risk factors affecting cognitive impairment of the elderly aged 65 and over: a cross-sectional study

F Han, C Luo, D Lv, L Tian, C Qu - Frontiers in aging neuroscience, 2022 - frontiersin.org
Objectives Elderly population with cognitive impairment has been accelerating in China.
This study aimed to explore the relationship between each risk factor and each cognitive …

Mild cognitive impairment and quality of life in the oldest old: a closer look

FS Hussenoeder, I Conrad, S Roehr, A Fuchs… - Quality of Life …, 2020 - Springer
Purpose Mild cognitive impairment (MCI) is a widespread phenomenon, especially affecting
older individuals. We will analyze in how far MCI affects different facets of quality of life …

Spatial-temporal dependency modeling and network hub detection for functional MRI analysis via convolutional-recurrent network

M Wang, C Lian, D Yao, D Zhang… - IEEE Transactions on …, 2019 - ieeexplore.ieee.org
Early identification of dementia at the stage of mild cognitive impairment (MCI) is crucial for
timely diagnosis and intervention of Alzheimer's disease (AD). Although several pioneering …

What are the association patterns between handgrip strength and adverse health conditions? A topical review

R McGrath, N Johnson, L Klawitter… - SAGE open …, 2020 - journals.sagepub.com
Measures of handgrip strength can be used to conveniently assess overall muscle strength
capacity. Although stand-alone measures of handgrip strength provide robust health …

Constituent isoflavones of Puerariae radix as a potential neuroprotector in cognitive impairment: evidence from preclinical studies

Y Ren, S Qu - Ageing research reviews, 2023 - Elsevier
With the increasing aging population worldwide, the incidence of senile cognitive
impairment (CI) is increasing, posing a serious threat to the health of elderly persons …