Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

Introduction: Depression is a multifactorial mood disorder with a high prevalence worldwide.
Until now, treatments for depression have focused on the inhibition of monoaminergic …

Depression has a multifactorial etiology that arises from environmental, psychological,
genetic, and biological factors. Environmental stress and genetic factors acting through …

Background Major depressive disorder is a serious psychiatric illness having serious
damaging effect on the quality of life of suffers. Quercetin is a plant flavonoid, mostly used as …

Naeem K, Tariq Al Kury L, Nasar F, et al. J Inflamm Res. 2021; 14: 1313–1329. At the
authors request, the Editor and Publisher of Journal of Inflammation Research wish to retract …

Olfactory bulbectomy (OB) is an animal model of depression that can mimic symptoms that
are characteristic of depressive patients, such as behavioral, neurochemical and …

In rodents, olfactory bulbectomy (OBX) results in several behavioral and biochemical
changes, useful as a screening model for antidepressants. Recent evidences suggest that …

Oxido-inflammatory aberrations play a substantial role in the pathophysiology of depression.
Oxido-inflammatory stress increases catabolism of tryptophan into kynurenine which leads …

Depression is a major emotional disorder that has a detrimental effect on quality of life. The
chronic mild stress (CMS)-depression model was adopted in rats to evaluate the …

Depression is a heterogeneous disorder and associated with inflammatory responses. The
influences of N-acetylcysteine (NAC) on neuroinflammation associated depression-like …