Immunoglobulin E (IgE) antibodies are well known for their role in mediating allergic
reactions, and their powerful effector functions activated through binding to Fc receptors …

Abstract In vertebrates, immunoglobulins (Igs), commonly known as antibodies, play an
integral role in the armamentarium of immune defense against various pathogens. After an …

We present an updated and integrated version of our widely used protein–protein docking
and binding affinity benchmarks. The benchmarks consist of non-redundant, high-quality …

This parameter was developed by the Joint Task Force on Practice Parameters,
representing the American Academy of Allergy, Asthma and Immunology, the American …

Purpose of review The purpose of this review is to evaluate the most recent findings on
indoor allergens and their impact on allergic diseases. Recent findings Indoor allergens are …

The development of allergic disease involves the production of IgE antibodies upon allergen
exposure in a process called sensitization. IgE binds to receptors on the surface of mast …

The structure determination of major allergens is a prerequisite for analyzing surface
exposed areas of the allergen and for map** conformational epitopes. These may be …

Immunoglobulin E (IgE) antibody is a critical effector molecule for adaptive allergen-induced
immune responses, which affect up to 40% of the population worldwide. Allergens are …

Among the vast number of identified protein families, allergens emanate from relatively few
families which translates to only a small fraction of identified protein families. In allergy …

Background Gene-environment interaction studies using genome-wide association study
data are often underpowered after adjustment for multiple comparisons. Differential gene …