One leading hypothesis suggests that memories are stored in ensembles of neurons (or
'engram cells') and that successful recall involves reactivation of these ensembles. A logical …

The predominant focus in the neurobiological study of memory has been on remembering
(persistence). However, recent studies have considered the neurobiology of forgetting …

Many aspects of the brain's design can be understood as the result of evolutionary drive
toward metabolic efficiency. In addition to the energetic costs of neural computation and …

It has been suggested that dopamine (DA) represents reward-prediction-error (RPE) defined
in reinforcement learning and therefore DA responds to unpredicted but not predicted …

Recent studies have identified molecular pathways driving forgetting and supported the
notion that forgetting is a biologically active process. The circuit mechanisms of forgetting …

Animals are required to handle daily massive amounts of information in an ever-changing
environment, and the resulting memories and experiences determine their survival and …

Some neural representations gradually change across multiple timescales. Here we argue
that modeling this “drift” could help explain the spacing effect (the long-term benefit of …