The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of
investigations of decision-making, behavioral flexibility, and social behavior. We review …

It is proposed that a cognitive map encoding the relationships between entities in the world
supports flexible behavior, but the majority of the neural evidence for such a system comes …

Arguably, the most difficult part of learning is deciding what to learn about. Should I
associate the positive outcome of safely completing a street-crossing with the situation 'the …

The prefrontal cortex (PFC) plays a critical role in the generation and regulation of emotion.
However, we lack an integrative framework for understanding how different emotion-related …

There is and has been a fruitful flow of concepts and ideas between studies of learning in
biological and artificial systems. Much early work that led to the development of …

Reversal learning paradigms are among the most widely used tests of cognitive flexibility
and have been used as assays, across species, for altered cognitive processes in a host of …

The outcome of a decision is often uncertain, and outcomes can vary over repeated
decisions. Whether decision outcomes should substantially affect behaviour and learning …

The number of papers about the orbitofrontal cortex (OFC) has grown from 1 per month in
1987 to a current rate of over 50 per month. This publication stream has implicated the OFC …

Orbitofrontal cortex (OFC) has long been known to play an important role in decision
making. However, the exact nature of that role has remained elusive. Here, we propose a …

Since the original characterization of the ventral visual pathway, our knowledge of its
neuroanatomy, functional properties, and extrinsic targets has grown considerably. Here we …