microRNA strand selection: Unwinding the rules
Abstract microRNAs (miRNAs) play a central role in the regulation of gene expression by
targeting specific mRNAs for degradation or translational repression. Each miRNA is post …
targeting specific mRNAs for degradation or translational repression. Each miRNA is post …
A uniform system for the annotation of vertebrate microRNA genes and the evolution of the human microRNAome
Although microRNAs (miRNAs) are among the most intensively studied molecules of the
past 20 years, determining what is and what is not a miRNA has not been straightforward …
past 20 years, determining what is and what is not a miRNA has not been straightforward …
miRBase: annotating high confidence microRNAs using deep sequencing data
A Kozomara, S Griffiths-Jones - Nucleic acids research, 2014 - academic.oup.com
We describe an update of the miRBase database (http://www. mirbase. org/), the primary
microRNA sequence repository. The latest miRBase release (v20, June 2013) contains 24 …
microRNA sequence repository. The latest miRBase release (v20, June 2013) contains 24 …
Genome-wide analysis of drosophila circular RNAs reveals their structural and sequence properties and age-dependent neural accumulation
Circularization was recently recognized to broadly expand transcriptome complexity. Here,
we exploit massive Drosophila total RNA-sequencing data,> 5 billion paired-end reads …
we exploit massive Drosophila total RNA-sequencing data,> 5 billion paired-end reads …
Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism
M Ouimet, S Koster, E Sakowski, B Ramkhelawon… - Nature …, 2016 - nature.com
Mycobacterium tuberculosis (Mtb) survives in macrophages by evading delivery to the
lysosome and promoting the accumulation of lipid bodies, which serve as a bacterial source …
lysosome and promoting the accumulation of lipid bodies, which serve as a bacterial source …
[HTML][HTML] Origins and mechanisms of miRNAs and siRNAs
RW Carthew, EJ Sontheimer - Cell, 2009 - cell.com
Over the last decade,∼ 20–30 nucleotide RNA molecules have emerged as critical
regulators in the expression and function of eukaryotic genomes. Two primary categories of …
regulators in the expression and function of eukaryotic genomes. Two primary categories of …
Evolution of microRNA diversity and regulation in animals
E Berezikov - Nature Reviews Genetics, 2011 - nature.com
In the past decade, microRNAs (miRNAs) have been uncovered as key regulators of gene
expression at the post-transcriptional level. The ancient origin of miRNAs, their dramatic …
expression at the post-transcriptional level. The ancient origin of miRNAs, their dramatic …
Regulation of the MIR155 host gene in physiological and pathological processes
TS Elton, H Selemon, SM Elton, NL Parinandi - Gene, 2013 - Elsevier
MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in
posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing …
posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing …
Uncovering small RNA-mediated responses to phosphate deficiency in Arabidopsis by deep sequencing
Recent studies have demonstrated the important role of plant microRNAs (miRNAs) under
nutrient deficiencies. In this study, deep sequencing of Arabidopsis (Arabidopsis thaliana) …
nutrient deficiencies. In this study, deep sequencing of Arabidopsis (Arabidopsis thaliana) …
The role of noncoding RNAs in Parkinson's disease: biomarkers and associations with pathogenic pathways
MC Kuo, SCH Liu, YF Hsu, RM Wu - Journal of biomedical science, 2021 - Springer
The discovery of various noncoding RNAs (ncRNAs) and their biological implications is a
growing area in cell biology. Increasing evidence has revealed canonical and noncanonical …
growing area in cell biology. Increasing evidence has revealed canonical and noncanonical …