Computational prediction of drug–target interactions (DTIs) has become an essential task in
the drug discovery process. It narrows down the search space for interactions by suggesting …

Age‐related central neurodegenerative diseases, such as Alzheimer's and Parkinson's
disease, are a rising public health concern and have been plagued by repeated drug …

To the Editor: Results from large-scale phenome-wide association studies (PheWAS) allow
association of genetic variants with a wide spectrum of human disorders and have provided …

Drug repositioning is a powerful method that can assists the conventional drug discovery
process by using existing drugs for treatment of a disease rather than its original indication …

Human dopamine (DA) transporter (hDAT) regulates dopaminergic signaling in the central
nervous system by maintaining the synaptic concentration of DA at physiological levels …

Drug repurposing (aka drug repositioning) is the search for new indications or molecular
targets distinct from a drug's putative activity, pharmacological effect or binding specificities …

Autophagy plays an essential role in cell survival/death and functioning. Modulation of
autophagy has been recognized as a promising therapeutic strategy against …

Identifying the interactions between drugs and target proteins is a key step in drug discovery.
This not only aids to understand the disease mechanism, but also helps to identify …

The bioengineering tools have significant advantages through less time-consuming and
utilized as a promising stage for the production of pharmaceutical bioproducts under the …