Genome engineering for crop improvement and future agriculture

C Gao - Cell, 2021 - cell.com
Feeding the ever-growing population is a major challenge, especially in light of rapidly
changing climate conditions. Genome editing is set to revolutionize plant breeding and …

Applications of CRISPR–Cas in agriculture and plant biotechnology

H Zhu, C Li, C Gao - Nature Reviews Molecular Cell Biology, 2020 - nature.com
The prokaryote-derived CRISPR–Cas genome editing technology has altered plant
molecular biology beyond all expectations. Characterized by robustness and high target …

Genome-edited powdery mildew resistance in wheat without growth penalties

S Li, D Lin, Y Zhang, M Deng, Y Chen, B Lv, B Li, Y Lei… - Nature, 2022 - nature.com
Disruption of susceptibility (S) genes in crops is an attractive breeding strategy for conferring
disease resistance,. However, S genes are implicated in many essential biological functions …

Weyl and Dirac semimetals in three-dimensional solids

NP Armitage, EJ Mele, A Vishwanath - Reviews of Modern Physics, 2018 - APS
Weyl and Dirac semimetals are three-dimensional phases of matter with gapless electronic
excitations that are protected by topology and symmetry. As three-dimensional analogs of …

Experimental perspective on three-dimensional topological semimetals

BQ Lv, T Qian, H Ding - Reviews of Modern Physics, 2021 - APS
Topological semimetals (TSMs) are characterized by bulk band crossings in their electronic
structures, which are expected to give rise to gapless electronic excitations and topological …

CRISPR/Cas genome editing and precision plant breeding in agriculture

K Chen, Y Wang, R Zhang, H Zhang… - Annual review of plant …, 2019 - annualreviews.org
Enhanced agricultural production through innovative breeding technology is urgently
needed to increase access to nutritious foods worldwide. Recent advances in CRISPR/Cas …

Heritable transgene-free genome editing in plants by grafting of wild-type shoots to transgenic donor rootstocks

L Yang, F Machin, S Wang, E Saplaoura… - Nature …, 2023 - nature.com
Generation of stable gene-edited plant lines using clustered regularly interspaced short
palindromic repeats (CRISPR)–CRISPR-associated protein 9 (Cas9) requires a lengthy …

The transcriptional landscape of polyploid wheat

RH Ramírez-González, P Borrill, D Lang… - Science, 2018 - science.org
INTRODUCTION Polyploidy, arising from whole-genome duplication or interspecific
hybridization, is ubiquitous across the plant and fungal kingdoms. The presence of highly …

Efficient DNA-free genome editing of bread wheat using CRISPR/Cas9 ribonucleoprotein complexes

Z Liang, K Chen, T Li, Y Zhang, Y Wang, Q Zhao… - Nature …, 2017 - nature.com
Substantial efforts are being made to optimize the CRISPR/Cas9 system for precision crop
breeding. The avoidance of transgene integration and reduction of off-target mutations are …

Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion

Y Zong, Y Wang, C Li, R Zhang, K Chen, Y Ran… - Nature …, 2017 - nature.com
Targeted base editing in plants without the need for a foreign DNA donor or double-stranded
DNA cleavage would accelerate genome modification and breeding in a wide array of crops …