The neurodevelopmental and dopamine hypotheses are leading theories of the
pathoetiology of schizophrenia, but they were developed in isolation. However, since they …

Mental illness modeling is still a major challenge for scientists. Animal models of
schizophrenia are essential to gain a better understanding of the disease etiopathology and …

Working memory (WM) is the ability to maintain and manipulate information 'in mind'. The
neural codes underlying WM have been a matter of debate. We simultaneously recorded the …

Cells selectively activated by a particular view of an environment have been found in the
primate hippocampus (HPC). Whether view cells are present in other brain areas, and how …

Uncontrollable stress exposure impairs working memory and reduces the firing of
dorsolateral prefrontal cortex (dlPFC)“Delay cells”, involving high levels of norepinephrine …

Neurons often encode highly heterogeneous non-linear functions of multiple task variables,
a signature of a high-dimensional geometry. We studied the representational geometry in …

Dysfunction of the cortical dorsal visual stream and visuospatial working memory (vsWM)
network in individuals with schizophrenia (SZ) likely reflects alterations in both excitatory …

Background Impairment in cognition is frequently associated with acute ketamine
administration. However, some questions remain unanswered as to which deficits are most …

Schizophrenia provides a quintessential disease model of how disturbances in the
molecular mechanisms of neurodevelopment lead to disruptions in the emergence of …

The hippocampus (HPC) and the lateral prefrontal cortex (LPFC) are two cortical areas of
the primate brain deemed essential to cognition. Here, we hypothesized that the codes …