Objectives To present historical and contemporary hypotheses on the pathogenesis of
benign prostatic hyperplasia (BPH), and the potential implications for current medical …

Prostate cancer remains the most frequently diagnosed cancer in men in North America, and
despite recent advances in treatment patients with metastatic disease continue to have poor …

Lung cancer is the leading cause of cancer mortality worldwide, and at only 18%, it has one
of the lowest 5-year survival rates of all malignancies. With its highly complex mutational …

CONTEXT: Metabolic syndrome (MetS), a cluster of several metabolic abnormalities with a
high socioeconomic cost, is considered a worldwide epidemic. Recent epidemiologic and …

Benign prostatic hyperplasia (BPH) is the most common urological disease in elderly men.
Epidemiological data suggest a causal link between this condition and prostatic …

Several different stimuli may induce chronic prostatic inflammation, which in turn would lead
to tissue damage and continuous wound healing, thus contributing to prostatic enlargement …

Self-DNA is present in the cytosol of many cancer cells and can promote effective immune
rejection of tumor cells, but the mechanisms leading to the presence of cytosolic DNA are …

Although the pathogenesis of BPH is not yet fully understood and several mechanisms seem
to be involved in the development and progression, recent studies strongly suggest that BPH …

Abstract In America and Western Europe, prostate cancer is the second leading cause of
death in men. Emerging evidence suggests that chronic inflammation is a major risk factor …

Benign prostatic hyperplasia (BPH) and prostate cancer are among the most common
diseases of the prostate gland and represent significant burdens for patients and health-care …