Advances in mass spectrometry imaging for spatial cancer metabolomics

X Ma, FM Fernández - Mass spectrometry reviews, 2024 - Wiley Online Library
Mass spectrometry (MS) has become a central technique in cancer research. The ability to
analyze various types of biomolecules in complex biological matrices makes it well suited for …

Unsupervised machine learning for exploratory data analysis in imaging mass spectrometry

N Verbeeck, RM Caprioli… - Mass spectrometry …, 2020 - Wiley Online Library
Imaging mass spectrometry (IMS) is a rapidly advancing molecular imaging modality that
can map the spatial distribution of molecules with high chemical specificity. IMS does not …

Ambient mass spectrometry imaging using direct liquid extraction techniques

J Laskin, I Lanekoff - Analytical chemistry, 2016 - ACS Publications
Mass spectrometry imaging (MSI) is a powerful analytical technique that enables label-free
spatial localization and identification of molecules in complex samples. 1− 4 MSI …

Faster, more reproducible DESI-MS for biological tissue imaging

J Tillner, V Wu, EA Jones, SD Pringle… - Journal of the …, 2017 - ACS Publications
A new, more robust sprayer for desorption electrospray ionization (DESI) mass spectrometry
imaging is presented. The main source of variability in DESI is thought to be the uncontrolled …

Review and perspectives on the applications of mass spectrometry imaging under ambient conditions

CJ Perez, AK Bagga, SS Prova… - Rapid …, 2019 - Wiley Online Library
Ambient mass spectrometry (AMS)‐based techniques are performed under ambient
conditions in which the ionization and desorption occur in the open environment allowing …

[HTML][HTML] Empowering the rapid authentication of the botanical origin of monofloral honey by coated blade spray mass spectrometry (CBS-MS)

A Tata, A Arrizabalaga-Larrañaga, A Massaro, R Stella… - Food Control, 2024 - Elsevier
In the quest for a rapid and cost-effective tool for determining the botanical origin of
monofloral honey, the analytical capabilities of coated blade spray mass spectrometry (CBS …

Ambient mass spectrometry for rapid authentication of milk from Alpine or lowland forage

A Tata, A Massaro, G Riuzzi, I Lanza, M Bragolusi… - Scientific Reports, 2022 - nature.com
Metabolomics approaches, such as direct analysis in real time-high resolution mass
spectrometry (DART-HRMS), allow characterising many polar and non-polar compounds …

Deep learning-based annotation transfer between molecular imaging modalities: an automated workflow for multimodal data integration

AM Race, D Sutton, G Hamm, G Maglennon… - Analytical …, 2021 - ACS Publications
An ever-increasing array of imaging technologies are being used in the study of complex
biological samples, each of which provides complementary, occasionally overlap** …

Ambient mass spectrometry in metabolomics

CS Clendinen, ME Monge, FM Fernández - Analyst, 2017 - pubs.rsc.org
Since the introduction of desorption electrospray ionization (DESI) mass spectrometry (MS),
ambient MS methods have seen increased use in a variety of fields from health to food …

Batch effects in MALDI mass spectrometry imaging

B Balluff, C Hopf, T Porta Siegel… - Journal of the …, 2021 - ACS Publications
Mass spectrometry imaging (MSI) has become an indispensible tool for spatially resolved
molecular investigation of tissues. One of the key application areas is biomedical research …